Prevalence of hand osteoarthritis and knee osteoarthritis in Kashin-Beck disease endemic areas and non Kashin-Beck disease endemic areas: A status survey. [PDF]
PLoS ONE, 2018 Osteoarthritis (OA) is a considerable health problem worldwide, and the prevalence of OA varies in different regions. In this study, the prevalence of OA in Kashin-Beck disease (KBD) and non-KBD endemic areas was examined, respectively.
Wei Lian +12 more
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Patients with Kashin-Beck Disease Obtained Lower Functional Activities but Better Satisfaction Than Patients with Osteoarthritis After Total Knee Arthroplasty: A Retrospective Study [PDF]
Clinical Interventions in Aging, 2022 Liangzhi Zhang,1 Hui Li,1,2 Lulu Bai,1,2 NaiChun Ji1 1Department of Sports Health Research Center, Xi ‘an Medical University, Xi’an City, People’s Republic of China; 2Department of Knee Surgery, Hong Hui Hospital, Xi’an Jiaotong University, Xi’an City ...
Zhang L, Li H, Bai L, Ji N
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Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease. [PDF]
PLoS Genetics, 2009 Kashin-Beck disease, a syndrome characterized by short stature, skeletal deformities, and arthropathy of multiple joints, is highly prevalent in specific regions of Asia.
Charlene M Downey +6 more
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BMC Medical Genetics, 2017 Background Many osteoarthritis (OA) susceptibility genes have been identified in recent years. Given the overlap in the phenotype of joint inflammation between OA and Kashin-Beck disease (KBD), the aim of this study is to explore whether the reported OA ...
Zhengfu Tai +9 more
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Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China [PDF]
Arthritis Research & Therapy, 2022 Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning +15 more
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The Status of Selenium and Zinc in the Urine of Children From Endemic Areas of Kashin-Beck Disease Over Three Consecutive Years [PDF]
Frontiers in Nutrition, 2022 Selenium deficiency is one of the main risk factors for Kashin-Beck disease (KBD). This study aimed to detect the status of selenium and zinc in the urine of children from endemic areas of KBD over three consecutive years and to evaluate whether selenium
Xin Kang +15 more
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Identification of energy metabolism and m6A-related gene clusters in Kashin-Beck disease based on bioinformatics analysis [PDF]
BMC Musculoskeletal DisordersKashin-Beck disease (KBD) is a chronic and debilitating osteoarthropathy predominantly affecting populations in certain endemic regions. Despite extensive research, the underlying mechanisms of KBD remain poorly understood.
Ao Zhou +6 more
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Correction: A study on atypical Kashin–Beck disease: an endemic ankle arthritis [PDF]
Journal of Orthopaedic Surgery and Research, 2023 Fang Qi +4 more
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Arthritis Research & Therapy, 2018 Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD ...
Yan Wen +10 more
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Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease [PDF]
Frontiers in Cell and Developmental BiologyObjectiveKashin-Beck disease (KBD) is a nutrition-related osteoarthropathy characterized by excessive apoptosis and matrix destruction. Micronutrient selenium (Se) deficiency is recognized as a major environmental risk factor.
Di Zhang +5 more
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