The Long‐term Efficacy of Total Knee Arthroplasty on End‐stage Kashin–Beck Disease of the Knee in Highland Tibetan Areas Patients: A Retrospective Study with 10‐Year Follow‐up [PDF]
Orthopaedic SurgeryObjective Despite the established success of total knee arthroplasty (TKA) with end‐stage osteoarthritis, there is a notable scarcity of research on its long‐term outcomes in individuals suffering from end‐stage Kashin–Beck disease (KBD).
Haocheng Sun +5 more
doaj +3 more sources
Effects of selenium and iodine on Kashin-Beck disease: an updated review [PDF]
Frontiers in NutritionKashin-Beck disease (KBD) is an endochondral osteogenesis disorder characterised by epiphysis damage and secondary deformable arthropathy induced by multiple external factors, among which selenium (Se) and iodine deficiency are important influencing ...
Lin Liu, Pan Luo, Pengfei Wen, Peng Xu
doaj +2 more sources
Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China [PDF]
Arthritis Research & Therapy, 2022 Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning +15 more
doaj +2 more sources
The Status of Selenium and Zinc in the Urine of Children From Endemic Areas of Kashin-Beck Disease Over Three Consecutive Years [PDF]
Frontiers in Nutrition, 2022 Selenium deficiency is one of the main risk factors for Kashin-Beck disease (KBD). This study aimed to detect the status of selenium and zinc in the urine of children from endemic areas of KBD over three consecutive years and to evaluate whether selenium
Xin Kang +15 more
doaj +2 more sources
Identification of energy metabolism and m6A-related gene clusters in Kashin-Beck disease based on bioinformatics analysis [PDF]
BMC Musculoskeletal DisordersKashin-Beck disease (KBD) is a chronic and debilitating osteoarthropathy predominantly affecting populations in certain endemic regions. Despite extensive research, the underlying mechanisms of KBD remain poorly understood.
Ao Zhou +6 more
doaj +2 more sources
Hydrochemical characteristics of surface waters and their relationships to the Kashin–Beck Disease in Longzi County, Tibet [PDF]
Scientific Reports, 2022 Although previous studies have been reported between the Kashin–Beck Disease (KBD) epidemic and the hydrochemical characteristics of surface waters, the etiology of the disease remains unclear.
Xinjie Zha +3 more
doaj +2 more sources
Prevalence of hand osteoarthritis and knee osteoarthritis in Kashin-Beck disease endemic areas and non Kashin-Beck disease endemic areas: A status survey. [PDF]
PLoS ONE, 2018 Osteoarthritis (OA) is a considerable health problem worldwide, and the prevalence of OA varies in different regions. In this study, the prevalence of OA in Kashin-Beck disease (KBD) and non-KBD endemic areas was examined, respectively.
Wei Lian +12 more
doaj +4 more sources
Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease [PDF]
Frontiers in Cell and Developmental BiologyObjectiveKashin-Beck disease (KBD) is a nutrition-related osteoarthropathy characterized by excessive apoptosis and matrix destruction. Micronutrient selenium (Se) deficiency is recognized as a major environmental risk factor.
Di Zhang +5 more
doaj +2 more sources
Correction: A study on atypical Kashin–Beck disease: an endemic ankle arthritis [PDF]
Journal of Orthopaedic Surgery and Research, 2023 Fang Qi +4 more
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Comparison of the responsiveness of the WOMAC and the 12-item WHODAS 2.0 in patients with Kashin–Beck disease [PDF]
BMC Musculoskeletal Disorders, 2020 Background Several questionnaires have been used to assess the health status of patients with Kashin-Beck disease (KBD) in clinical trials, but the evidence regarding the responsiveness of these instruments in KBD patients is limited.
Lei Yang +5 more
doaj +2 more sources