Results 41 to 50 of about 1,047 (156)

Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis

Arthritis Research & Therapy, 2018
Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD ...
Yan Wen, Ping Li, Jingcan Hao, Chen Duan, Jing Han, Awen He, Yanan Du, Li Liu, Xiao Liang, Feng Zhang, Xiong Guo   +10 more
doaj   +1 more source

Kashin-Beck disease: a historical overview [PDF]

International Orthopaedics, 2001
In 1919, the first report on Kashin-Beck disease (KBD) made by a Japanese doctor described an endemic occurrence in the northern district of Korea. In the 1930s, Dr. Takamori and his colleagues at Manchuria Medical College produced a series of reports on its endemiology, clinical and roentgenological findings observed in the north-eastern district of ...
openaire   +2 more sources

Kashin-Beck disease involving the ankles

Radiology Case Reports, 2011
We present a case of Kashin-Beck Disease primarily affecting the ankles. Our findings are consistent with other reports of the symptoms, incidence, and progression of these diseases. At this time, our patient has chosen conservative treatment, but is considering eventual osteoarticular allografts.
Niebulski, Hannah Z., Richardson, Michael L.   +1 more
openaire   +2 more sources

Spatial distribution and determinants of health loss from Kashin-Beck disease in Bin County, Shaanxi Province, China

BMC Public Health, 2021
Background Kashin-Beck disease (KBD) is one of the major endemic diseases in China, which severely impacts the physical health and life quality of people.
Jing Wang, Xiaoya Wang, Hairong Li, Linsheng Yang, Yingchun Li, Chang Kong   +5 more
doaj   +1 more source

Osteotomy at the knee for advanced cases of Kashin-Beck disease [PDF]

International Orthopaedics, 1998
The results of 247 osteotomies at the knee were analysed in 195 patients with Kashin-Beck disease. Since 1983, 37 varus and 210 valgus deformities have been operated on. Supracondylar osteotomy was carried out so that there is a cortical spike in the distal metaphysis which is impacted into the femoral condyle.
F D, Liu, Z L, Wang, M, Hinsenkamp
openaire   +2 more sources

Cytotoxic Properties of HT-2 Toxin in Human Chondrocytes: Could T₃ Inhibit Toxicity of HT-2?

Toxins, 2019
Thyroid hormone triiodothyronine (T3) plays an important role in coordinated endochondral ossification and hypertrophic differentiation of the growth plate, while aberrant thyroid hormone function appears to be related to skeletal malformations ...
Feng’e Zhang, Mikko Juhani Lammi, Wanzhen Shao, Pan Zhang, Yanan Zhang, Haiyan Wei, Xiong Guo   +6 more
doaj   +1 more source

Whole-exome sequencing for the identification of susceptibility genes of Kashin-Beck disease.

PLoS ONE, 2014
ObjectiveTo identify and investigate the susceptibility genes of Kashin-Beck disease (KBD) in Chinese population.MethodsWhole-exome capturing and sequencing technology was used for the detection of genetic variations in 19 individuals from six families ...
Zhenxing Yang, Yu Xu, Hongrong Luo, Xiaohong Ma, Qiang Wang, Yingcheng Wang, Wei Deng, Tao Jiang, Guangqing Sun, Tingting He, Jingchu Hu, Yingrui Li, Jun Wang, Tao Li, Xun Hu   +14 more
doaj   +1 more source

Kashin-Beck disease and drinking water in Central Tibet [PDF]

International Orthopaedics, 2001
A cross-sectional survey was carried out in order to study the relationship between Kashin-Beck disease and drinking water. The average volume of the water containers was larger in families unaffected by the disease. Organic material was measured by ultraviolet (UV) spectroscopy. The UV absorbency was significantly lower in drinking water of unaffected
M, La Grange, F, Mathieu, F, Begaux, C, Suetens, M C, Durand   +4 more
openaire   +2 more sources

Unlocking the Nutritional Potential of Gamma Amino Butyric Acid (GABA) Rice: Towards a Sustainable Approach to Metabolic Disorder Remedies

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
This study addresses the critical issue of nutrient deficiencies associated with the widespread consumption of conventional milled rice, which often lacks essential vitamins and minerals due to the removal of the bran layer during processing. It demonstrated that controlled germination of paddy rice, followed by parboiling, substantially increases the ...
Uloma E. Onyeka, Ekpeno Sunday Ukpong, Chinedu B. Azudialu, Sali A. Ndindeng, Kalimuthu Senthilkumar, Christian O. Dimkpa   +5 more
wiley   +1 more source

Chemical composition of natural waters from the Urov endemic area

Desalination and Water Treatment
Owing to the importance of drinking water in human nutrition, in this study, we performed a comparative analysis of the chemical composition of drinking water from settlements endemic to Kashin–Beck disease and from territories that are not endemic to ...
Vadim Ermakov, Vladimir Safonov, Valentina Danilova, Uliana Gulyaeva, Sergey Tyutikov   +4 more
doaj   +1 more source