Results 41 to 50 of about 5,423,374 (131)

Osteoarthritis Deformans Endemica: Etiology, Diagnosis, Treatment, Prevention

Bolʹ, Sustavy, Pozvonočnik, 2012
The paper deals with generalization of historical, epidemiological, etiologic, diagnostic, preventive and therapeutic data of osteoarthritis deformans endemica (Kashin — Beck disease). Taking into account the growing trend of deterioration of the current
T.V. Frolova, О.V. Okhapkina, Yu.V. Sorokolat, Ye.G. Koleushko   +3 more
doaj   +1 more source

Comparison of the responsiveness of the WOMAC and the 12-item WHODAS 2.0 in patients with Kashin–Beck disease

BMC Musculoskeletal Disorders, 2020
Background Several questionnaires have been used to assess the health status of patients with Kashin-Beck disease (KBD) in clinical trials, but the evidence regarding the responsiveness of these instruments in KBD patients is limited.
Lei Yang, Dimiao Wang, Xiuxia Li, Hangjing Yuan, Hua Fang, Xiong Guo   +5 more
doaj   +1 more source

SIRT1/PGC-1α-regulated mitochondrial biogenesis is involved in T-2 toxin-induced chondrocyte injury

Ecotoxicology and Environmental Safety
T-2 toxin, a type A trichothecene mycotoxin, has been implicated as an environmental risk factor for Kashin-Beck disease (KBD), an endemic osteoarthropathy characterized by cartilage damage.
Chenxi Wang, Junfeng Zhou, Weichang Zhang, Yue Zhao, Jiaxin Li, Jiayuan Li, Jun Yu, Silu Cui   +7 more
doaj   +1 more source

Spatial distribution and determinants of health loss from Kashin-Beck disease in Bin County, Shaanxi Province, China

BMC Public Health, 2021
Background Kashin-Beck disease (KBD) is one of the major endemic diseases in China, which severely impacts the physical health and life quality of people.
Jing Wang, Xiaoya Wang, Hairong Li, Linsheng Yang, Yingchun Li, Chang Kong   +5 more
doaj   +1 more source

Histology of Kashin-Beck lesions.

, 2001
There are few papers in existence describing the histopathology of Kashin-Beck disease. The few existing papers mention chondronecrosis within the epiphyseal primodium and metaphyseal cartilage.
Hinsenkamp, Maurice, Pasteels, Jean Lambert, Perlmutter, Noemi, Liu, F.-D., Rooze, Marcel, Mathieu, Françoise   +5 more
core   +1 more source

Cytotoxic Properties of HT-2 Toxin in Human Chondrocytes: Could T₃ Inhibit Toxicity of HT-2?

Toxins, 2019
Thyroid hormone triiodothyronine (T3) plays an important role in coordinated endochondral ossification and hypertrophic differentiation of the growth plate, while aberrant thyroid hormone function appears to be related to skeletal malformations ...
Feng’e Zhang, Mikko Juhani Lammi, Wanzhen Shao, Pan Zhang, Yanan Zhang, Haiyan Wei, Xiong Guo   +6 more
doaj   +1 more source

Clinical manifestations of Kashin-Beck disease in Nyemo Valley, Tibet.

, 1997
Clinical manifestations of Kashin-Beck disease have been studied in Central Tibet. Statistical analysis of physical signs allowed a definition of the clinical diagnosis and a scale for the functional severity for the disease to be drawn up.
Begaux, Françoise, Lan, Z Y, Hinsenkamp, Maurice, Mathieu, F, Begaux, F, Suetens, C., Suetens, C, Mathieu, Françoise, Hinsenkamp, M   +8 more
core   +1 more source

Chemical composition of natural waters from the Urov endemic area

Desalination and Water Treatment
Owing to the importance of drinking water in human nutrition, in this study, we performed a comparative analysis of the chemical composition of drinking water from settlements endemic to Kashin–Beck disease and from territories that are not endemic to ...
Vadim Ermakov, Vladimir Safonov, Valentina Danilova, Uliana Gulyaeva, Sergey Tyutikov   +4 more
doaj   +1 more source

COL9A1 gene polymorphism is associated with Kashin-Beck disease in a northwest Chinese Han population. [PDF]

PLoS ONE, 2015
OBJECTIVE: We sought to determine whether genomic polymorphism in collagen IX genes (COL9A) was associated with Kashin-Beck disease (KBD). METHODS: Twenty seven single nucleotide polymorphisms (SNPs) in COL9AI, COL9A2 and COL9A3 were genotyped in 274 KBD
Xiaowei Shi, Feng Zhang, Aili Lv, Yan Wen, Xiong Guo   +4 more
doaj   +1 more source

Investigation of selenium nutritional status and dietary pattern among children in Kashin-Beck disease endemic areas in Shaanxi Province, China using duplicate portion sampling method

Environment International, 2022
Background and objectives: Selenium deficiency is a primary risk factor of Kashin-Beck disease (KBD). This study aimed to investigate whether children in endemic areas could maintain sufficient selenium intake after termination of selenium supplement ...
Yujie Ning, Minhan Hu, Sijie Chen, Feiyu Zhang, Xiaodong Yang, Qingping Zhang, Yi Gong, Ruitian Huang, Yanli Liu, Feihong Chen, Leilei Pei, Xiong Guo, Lianke Kang, Xinyi Wang, Yan Zhang, Xi Wang   +15 more
doaj   +1 more source