Results 31 to 40 of about 1,061 (155)

The urinary levels of CTX-II, C2C, PYD, and Helix-II increased among adults with KBD: a cross-sectional study

Journal of Orthopaedic Surgery and Research, 2019
Background Kashin-Beck disease (KBD) is an endemic osteoarthropathy, and its pathogenesis is still not entirely clear. Pathologically, many KBD changes are similar to those of osteoarthritis (OA).
Quan Quan Song, Li Yan Sun, Chun Hui Li, Yu Jiao Liu, Si Lu Cui, Yun Qi Liu, Yan Hong Cao, Jun Rui Pei, Yue Wang, Wei Lian, Zhe Jiao, Qing Deng, Jun Yu   +12 more
doaj   +1 more source

Kashin-Beck disease [PDF]

International Orthopaedics, 2001
info:eu-repo/semantics ...
openaire   +4 more sources

Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease

Journal of Orthopaedic Surgery and Research, 2018
Background Kashin-Beck disease (KBD) is an endemic, chronic, degenerative osteoarthropathy. KBD is usually diagnosed by using X-ray image and clinical symptoms, lacking of serological biomarkers.
Wei Lian, Hui Liu, Li Yan Sun, Yun Qi Liu, Si Lu Cui, Yue Wang, Quan Quan Song, Qing Deng, Shao Ping Wang, Yan Hong Cao, Xue Ying Zhang, Yuan Yuan Jiang, Hong Yan Lv, Li Bin Duan, Jun Yu   +14 more
doaj   +1 more source

The prevalence of mycotoxins in Kashin-Beck disease [PDF]

International Orthopaedics, 2001
Mycotoxins are naturally occurring toxic chemical compounds produced by fungi infesting agricultural crops both during their growth and storage. Such secondary metabolites, when ingested, can produce toxic syndromes in humans. As it has been suggested that mycotoxins might be involved in the development of Kashin-Beck disease (KBD), we undertook a ...
Haubruge, Éric, Chasseur, Camille, Debouck, Catherine, Begaux, Françoise, Suetens, C., Mathieu, Françoise, Michel, Véronique, Gaspar, Clara, Rooze, Marcel, Hinsenkamp, Maurice, Gillet, P., Tintigner, Nicole, Lognay, Georges C.   +12 more
openaire   +3 more sources

Kashin-Beck disease and iodine deficiency in Tibet [PDF]

International Orthopaedics, 2001
We evaluated iodine and selenium status in 575 children between 5 and 15 years with Kashin-Beck disease from endemic and non-endemic areas. Of these 267 (46%) children had goiter. The proportion of subjects with goiter was higher in the villages with Kashin-Beck disease than in the control village. In the villages with Kashin-Beck disease, 105 (23%) of
Moreno-Reyes, R., Suetens, C., Mathieu, F., Begaux, F., Dun Zhu,, Rivera, T., Boelaert, M., Nève, J., Perlmutter, N., Vanderpas, J.   +9 more
openaire   +3 more sources

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease

BMC Musculoskeletal Disorders, 2012
Background Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions remains unclear, there is not ...
Zhang Feng, Guo Xiong, Wang Weizhuo, Wu Shixun, Ma Weijuan, Yan Hua   +5 more
doaj   +1 more source

Cold weather and Kashin-Beck disease

Frigid Zone Medicine, 2023
Abstract Kashin-Beck disease (KBD) is an endemic osteoarthropathy. Its distribution region covers a long and narrow belt on the Pacific side and belongs to continental climate with short summer, long frost period, and large temperature differences between day and night.
Wang Kewei, Yu Jun, Sun Dianjun
openaire   +2 more sources

Osteoarthritis Deformans Endemica: Etiology, Diagnosis, Treatment, Prevention

Bolʹ, Sustavy, Pozvonočnik, 2012
The paper deals with generalization of historical, epidemiological, etiologic, diagnostic, preventive and therapeutic data of osteoarthritis deformans endemica (Kashin — Beck disease). Taking into account the growing trend of deterioration of the current
T.V. Frolova, О.V. Okhapkina, Yu.V. Sorokolat, Ye.G. Koleushko   +3 more
doaj   +1 more source

Animal models of Kashin-Beck disease exposed to environmental risk factors: Methods and comparisons

Ecotoxicology and Environmental Safety, 2022
The main etiological mechanism for Kashin-Beck disease (KBD) is deep chondrocyte necrosis induced by environmental risk factors (ERFs). The scholars have conducted several epidemiological, cellular, and animal model studies on ERFs.
Fang-fang Yu, Juan Zuo, Lei Sun, Shui-yuan Yu, Xiao-li Lei, Jun-hua Zhu, Guo-yu Zhou, Xiong Guo, Yue Ba   +8 more
doaj   +1 more source

Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis

Arthritis Research & Therapy, 2018
Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD ...
Yan Wen, Ping Li, Jingcan Hao, Chen Duan, Jing Han, Awen He, Yanan Du, Li Liu, Xiao Liang, Feng Zhang, Xiong Guo   +10 more
doaj   +1 more source