Results 31 to 40 of about 2,554 (202)

The urinary levels of CTX-II, C2C, PYD, and Helix-II increased among adults with KBD: a cross-sectional study

Journal of Orthopaedic Surgery and Research, 2019
Background Kashin-Beck disease (KBD) is an endemic osteoarthropathy, and its pathogenesis is still not entirely clear. Pathologically, many KBD changes are similar to those of osteoarthritis (OA).
Quan Quan Song, Li Yan Sun, Chun Hui Li, Yu Jiao Liu, Si Lu Cui, Yun Qi Liu, Yan Hong Cao, Jun Rui Pei, Yue Wang, Wei Lian, Zhe Jiao, Qing Deng, Jun Yu   +12 more
doaj   +1 more source

Selenium in biology: Facts and medical perspectives [PDF]

, 2000
Several decades after the discovery of setenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21(st) proteinogenic amino acid, selenocysteine, have been identified ...
Brigelius-Flohé, Regina, Böck, August, Flohé, Leopold, Gärtner, Roland, Köhrle, Josef, Meyer, Ortwin   +5 more
core   +1 more source

Kashin-Beck disease [PDF]

International Orthopaedics, 2001
Guest Editorial ; info:eu-repo/semantics ...
openaire   +2 more sources

Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease

Journal of Orthopaedic Surgery and Research, 2018
Background Kashin-Beck disease (KBD) is an endemic, chronic, degenerative osteoarthropathy. KBD is usually diagnosed by using X-ray image and clinical symptoms, lacking of serological biomarkers.
Wei Lian, Hui Liu, Li Yan Sun, Yun Qi Liu, Si Lu Cui, Yue Wang, Quan Quan Song, Qing Deng, Shao Ping Wang, Yan Hong Cao, Xue Ying Zhang, Yuan Yuan Jiang, Hong Yan Lv, Li Bin Duan, Jun Yu   +14 more
doaj   +1 more source

Are there functional consequences of a reduction in selenium intake in UK subjects? [PDF]

, 2004
Dietary Se levels in the UK have fallen over the last 20 years and recent surveys indicate that average Se intakes are 30-40 microg/d, which is well below the current UK reference nutrient intake for adult men (75 microg/d) or women (60 microg/d ...
Anne McArdle, Beck, Bonomini, Broome, Burk, C. Anthony Hart, Caroline S. Broome, Francis McArdle, Gasparian, Ge, Malcolm J. Jackson, Olivieri, Peretz, Stephanie A. Dillon   +13 more
core   +1 more source

Cold weather and Kashin-Beck disease

Frigid Zone Medicine, 2023
Abstract Kashin-Beck disease (KBD) is an endemic osteoarthropathy. Its distribution region covers a long and narrow belt on the Pacific side and belongs to continental climate with short summer, long frost period, and large temperature differences between day and night.
Wang Kewei, Yu Jun, Sun Dianjun
openaire   +2 more sources

Reprogramming of Mitochondrial Respiratory Chain Complex by Targeting SIRT3‐COX4I2 Axis Attenuates Osteoarthritis Progression

Advanced Science, Volume 10, Issue 10, April 5, 2023., 2023
The SIRT3‐medicated post‐translational acetylation of the mitochondrial respiratory chain has therapeutic potential for the treatment of osteoarthritis (OA). Mechanistically, SIRT3 directly binds and deacetylates COX4I2 to promote mitochondrial respiration activity.
Yijian Zhang, Yang Liu, Mingzhuang Hou, Xiaowei Xia, Junlin Liu, Yong Xu, Qin Shi, Zhongmin Zhang, Liang Wang, Yifan Shen, Huilin Yang, Fan He, Xuesong Zhu   +12 more
wiley   +1 more source

Pathways related to mitochondrial dysfunction in cartilage of endemic osteoarthritis patients in China [PDF]

, 2012
n this paper, we present the first evidence of differences in the mitochondria-related gene expression profiles of adult articular cartilage derived from patients with Kashin-Beck disease and normal controls.
B. W. Gibson, C. Brenner, C. Duan, C. M. Downey, ChunYan Li, D. C. Wallace, D. R. Green, Feng Zhang, G. A. Cortopassi, H. M. Lee, H. Zou, I. Shokolenko, J. Andrews, J. D. Robertus, J. M. Jurgensmeier, J. Mikko Lammi, J. T. Liu, M. C. Sugden, R. A. Butow, R. G. Mehta, R. Moreno-Reyes, S. J. Wang, S. Malladi, T. Chittenden, T. Shi, W. C. Hawkes, W. Z. Wang, WeiJuan Ma, WeiZhuo Wang, X. Bai, X. Guo, Xiong Guo, Y. Hatefi, Y. M. Xiong, YiDong Bai, YinGang Zhang, YouFen Li   +36 more
core   +1 more source

Alternaria in food: Ecophysiology, mycotoxin production and toxicology [PDF]

, 2015
Alternaria species are common saprophytes or pathogens of a wide range of plants pre- and post-harvest. This review considers the relative importance of Alternaria species, their ecology, competitiveness, production of mycotoxins and the prevalence of ...
Lee, Hyang Burm, Magan, Naresh, Patriarca, Andrea   +2 more
core   +2 more sources

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease

BMC Musculoskeletal Disorders, 2012
Background Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions remains unclear, there is not ...
Zhang Feng, Guo Xiong, Wang Weizhuo, Wu Shixun, Ma Weijuan, Yan Hua   +5 more
doaj   +1 more source