Results 31 to 40 of about 1,047 (156)
Prevalence and Risk Factors of Depression in Patients With Endemic Osteoarthritis Kashin-Beck Disease. [PDF]
Depress AnxietyBackground: Kashin–Beck disease (KBD) is an endemic osteoarthropathy, which occurs in children aged 3–12, with similarity to osteoarthritis (OA). Previous studies have shown significant depression symptoms in OA patients, yet no comparable research has been conducted in KBD patients. Methods: We conducted a field investigation in KBD areas in Northwest
Liu Y +12 more
europepmc +2 more sources
Transcriptome-wide RNA m6A methylation profiles in an endemic osteoarthropathy, Kashin-Beck disease. [PDF]
J Cell Mol MedAbstract Kashin‐Beck disease (KBD) is a chronic degenerative, disabling disease of the bones and joints and its exact aetiology and pathogenesis remain uncertain. This study is to investigate the role of m6A modification in the pathogenesis of KBD. Combined analysis of m6A MeRIP‐Seq and RNA‐Seq were used to analyse human peripheral blood samples from ...
Zhang Q +9 more
europepmc +2 more sources
Journal of Orthopaedic Surgery and Research, 2018 Background Kashin-Beck disease (KBD) is an endemic, chronic, degenerative osteoarthropathy. KBD is usually diagnosed by using X-ray image and clinical symptoms, lacking of serological biomarkers.
Wei Lian +14 more
doaj +1 more source
The prevalence of mycotoxins in Kashin-Beck disease [PDF]
International Orthopaedics, 2001 Mycotoxins are naturally occurring toxic chemical compounds produced by fungi infesting agricultural crops both during their growth and storage. Such secondary metabolites, when ingested, can produce toxic syndromes in humans. As it has been suggested that mycotoxins might be involved in the development of Kashin-Beck disease (KBD), we undertook a ...
Haubruge, Éric +12 more
openaire +3 more sources
Kashin-Beck disease and iodine deficiency in Tibet [PDF]
International Orthopaedics, 2001 We evaluated iodine and selenium status in 575 children between 5 and 15 years with Kashin-Beck disease from endemic and non-endemic areas. Of these 267 (46%) children had goiter. The proportion of subjects with goiter was higher in the villages with Kashin-Beck disease than in the control village. In the villages with Kashin-Beck disease, 105 (23%) of
Moreno-Reyes, R. +9 more
openaire +3 more sources
BMC Musculoskeletal Disorders, 2012 Background Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions remains unclear, there is not ...
Zhang Feng +5 more
doaj +1 more source
Cold weather and Kashin-Beck disease
Frigid Zone Medicine, 2023 Abstract Kashin-Beck disease (KBD) is an endemic osteoarthropathy. Its distribution region covers a long and narrow belt on the Pacific side and belongs to continental climate with short summer, long frost period, and large temperature differences between day and night.
Wang Kewei, Yu Jun, Sun Dianjun
openaire +2 more sources
Osteoarthritis Deformans Endemica: Etiology, Diagnosis, Treatment, Prevention
Bolʹ, Sustavy, Pozvonočnik, 2012 The paper deals with generalization of historical, epidemiological, etiologic, diagnostic, preventive and therapeutic data of osteoarthritis deformans endemica (Kashin — Beck disease). Taking into account the growing trend of deterioration of the current
T.V. Frolova +3 more
doaj +1 more source
Animal models of Kashin-Beck disease exposed to environmental risk factors: Methods and comparisons
Ecotoxicology and Environmental Safety, 2022 The main etiological mechanism for Kashin-Beck disease (KBD) is deep chondrocyte necrosis induced by environmental risk factors (ERFs). The scholars have conducted several epidemiological, cellular, and animal model studies on ERFs.
Fang-fang Yu +8 more
doaj +1 more source