Results 31 to 40 of about 5,423,374 (131)

The urinary levels of CTX-II, C2C, PYD, and Helix-II increased among adults with KBD: a cross-sectional study

Journal of Orthopaedic Surgery and Research, 2019
Background Kashin-Beck disease (KBD) is an endemic osteoarthropathy, and its pathogenesis is still not entirely clear. Pathologically, many KBD changes are similar to those of osteoarthritis (OA).
Quan Quan Song, Li Yan Sun, Chun Hui Li, Yu Jiao Liu, Si Lu Cui, Yun Qi Liu, Yan Hong Cao, Jun Rui Pei, Yue Wang, Wei Lian, Zhe Jiao, Qing Deng, Jun Yu   +12 more
doaj   +1 more source

Selenium and iodine supplementation of rural Tibetan children affected by Kashin-Beck osteoarthropathy [PDF]

, 2003
Background: Kashin-Beck disease is an osteoarthropathy endemic in selenium- and iodine-deficient areas around Lhasa, Tibet. Objective: We assessed the efficacy of selenium supplementation on disease progression.
Boelaert, M, Carl Suetens, Vanderpas, J, Mathieu, F, Perlmutter, N, Moreno Reyes, Mario Rodrigo, Françoise Mathieu, Suetens, C, Perlmutter, N., Moreno-Reyes, R, Rivera, M. T., Perlmutter, Noemi, Françoise Begaux, Nève, J, Boelaert, M., Moreno-Reyes, R., Jean Nève, Boelaert, Marleen, Begaux, Françoise, Nève, J., Begaux, F., Rivera, T., Suetens, C., Mathieu, F., Rodrigo Moreno-Reyes, Jean Vanderpas, Vanderpas, Jean-Baptiste, Marleen Boelaert, Noémi Perlmutter, Rivera, M, Maria T Rivera, Neve, Jean, Begaux, F, Vanderpas, J., Mathieu, Françoise   +34 more
core   +1 more source

Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease

Journal of Orthopaedic Surgery and Research, 2018
Background Kashin-Beck disease (KBD) is an endemic, chronic, degenerative osteoarthropathy. KBD is usually diagnosed by using X-ray image and clinical symptoms, lacking of serological biomarkers.
Wei Lian, Hui Liu, Li Yan Sun, Yun Qi Liu, Si Lu Cui, Yue Wang, Quan Quan Song, Qing Deng, Shao Ping Wang, Yan Hong Cao, Xue Ying Zhang, Yuan Yuan Jiang, Hong Yan Lv, Li Bin Duan, Jun Yu   +14 more
doaj   +1 more source

Research Progress of Drinking Water and Trace Elements in KBD Area [PDF]

, 2023
Kaschin-beck disease (KBD) is an endemic, chronic, and deformable osteochondral disease characterized by multiple degenerations and deep cell necrosis of epiphysis, epiphysis, and articular cartilage.
Kou, Jiushe, Jiushe Kou, Huang, Tianjiao, Tianjiao Huang   +3 more
core   +1 more source

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease

BMC Musculoskeletal Disorders, 2012
Background Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions remains unclear, there is not ...
Zhang Feng, Guo Xiong, Wang Weizhuo, Wu Shixun, Ma Weijuan, Yan Hua   +5 more
doaj   +1 more source

Table1_Differential expression of cyclins CCNB1 and CCNG1 is involved in the chondrocyte damage of kashin-beck disease.DOCX

, 2022
The purpose of this study was clarify the relationship between the differential expression of cyclins CCNB1 and CCNG1 and chondrocyte damage in Kashin-Beck disease. Systematic review and high-throughput sequencing of chondrocytes derived from Kashin-Beck
Shaniya Nuer (14255816), Kaidiriye Setiwalidi (14255810), Shujin Li (313783), Ruitian Huang (11929325), Hongmou Zhao (3698644), Yanli Liu (198140), Feihong Chen (1541692), Jialei Fu (13173423), He Hei (14255813), Yi Gong (160525), Xiong Guo (189516), Yifan Wu (1702936), Junyi Liu (1801294), Feiyu Zhang (499750), Chaowei Wang (5832398), Minhan Hu (11929319), Xi Wang (15032), Yujie Ning (6339635), Tianxiao Zhang (172364), Sijie Chen (1622476)   +19 more
core   +1 more source

Image1_Differential expression of cyclins CCNB1 and CCNG1 is involved in the chondrocyte damage of kashin-beck disease.JPEG

, 2022
The purpose of this study was clarify the relationship between the differential expression of cyclins CCNB1 and CCNG1 and chondrocyte damage in Kashin-Beck disease. Systematic review and high-throughput sequencing of chondrocytes derived from Kashin-Beck
Shaniya Nuer (14255816), Kaidiriye Setiwalidi (14255810), Shujin Li (313783), Ruitian Huang (11929325), Hongmou Zhao (3698644), Yanli Liu (198140), Feihong Chen (1541692), Jialei Fu (13173423), He Hei (14255813), Yi Gong (160525), Xiong Guo (189516), Yifan Wu (1702936), Junyi Liu (1801294), Feiyu Zhang (499750), Chaowei Wang (5832398), Minhan Hu (11929319), Xi Wang (15032), Yujie Ning (6339635), Tianxiao Zhang (172364), Sijie Chen (1622476)   +19 more
core   +1 more source

Animal models of Kashin-Beck disease exposed to environmental risk factors: Methods and comparisons

Ecotoxicology and Environmental Safety, 2022
The main etiological mechanism for Kashin-Beck disease (KBD) is deep chondrocyte necrosis induced by environmental risk factors (ERFs). The scholars have conducted several epidemiological, cellular, and animal model studies on ERFs.
Fang-fang Yu, Juan Zuo, Lei Sun, Shui-yuan Yu, Xiao-li Lei, Jun-hua Zhu, Guo-yu Zhou, Xiong Guo, Yue Ba   +8 more
doaj   +1 more source

Proteoglycan metabolism, cell death and Kashin-Beck Disease [PDF]

, 2012
Kashin-Beck Disease (KBD) is an endemic, chronic and degenerative osteoarthropathy principally occurring in children. The characteristic pathological change of KBD is chondrocyte necrosis in hyaline articular cartilage.
Siyuan Li, Caterson, Bruce, Bruce Caterson, Junling Cao, Clare E. Hughes, Li, Siyuan, Hughes, Clare Elizabeth, Cao, Junling   +7 more
core   +1 more source

Cold weather and Kashin-Beck disease

, 2023
Kashin-Beck disease (KBD) is an endemic osteoarthropathy. Its distribution region covers a long and narrow belt on the Pacific side and belongs to continental climate with short summer, long frost period, and large temperature differences between day and
Yu Jun, Wang Kewei, Sun Dianjun, Jun Yu, Dianjun Sun, Kewei Wang   +5 more
core   +1 more source