Results 61 to 70 of about 1,324,564 (290)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2014 Citation: 'trace element' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.T06421 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
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Spectral characterization of sums of commutators II
, 1997 For countably generated ideals, $\Jc$, of $B(\Hil)$, geometric stability is necessary for the canonical spectral characterization of sums of $(\Jc,B(\Hil))$--commutators to hold. This answers a question raised by Dykema, Figiel, Weiss and Wodzicki. There
Dykema, Kenneth J., Kalton, Nigel J.
core +3 more sources
Mesolithic Human Bones from the Upper Volga Basin: Radiocarbon and Trace Elements [PDF]
, 2009 Human bones from 3 Mesolithic sites in the Upper Volga basin were analyzed for trace elements, and dated by accelerator mass spectrometry (AMS). The radiocarbon dates of the bones correspond to the Mesolithic era.
Alexandrovskaya, E.I., +3 more
core +4 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Translational Psychiatry, 2023 The aim of this study was to investigate the possible interaction of mitochondrial dysfunction and inflammatory cytokines in the risk of anxiety and depression. We utilized the UK Biobank for the sample of this study.
Li Liu +14 more
doaj +1 more source
Trace Element Estimation – Methods & Clinical Context [PDF]
, 2005 Understanding the effects of trace metals on human health is as complex as it is fascinating. As mentioned earlier, the high concentrations may prove toxic, as also, depletion in the concentration of the essential trace elements may cause various ...
Rao Nanjunda, Dr. Ananth
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Фармакокинетика и Фармакодинамика, 2017 Group B vitamins are characterized by neuroprotective effects. Mechanisms of action of synergistic combinations of various vitamins are insufficiently studied.
O. A. Gromov +2 more
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