Results 61 to 70 of about 368,022 (299)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Trace evidence: Here today, gone tomorrow?
, 2010 The recent report of the National Research Council of the US National Academies "Strengthening Forensic Science in the United States: a Path Forward" found evidence that the level of scientific development and evaluation varies substantially among the ...
Robertson, James (R18070) +4 more
core +1 more source
The Methods of Extracting Trace Evidence in Criminal Investigation
, 2022 Among the types of evidence collected from the crime scene, the trace is one of the necessary evidences that need to take into consideration during crime scene investigation. A well known accepted principle in criminalistics “Every contact leaves a trace”
ROBINO D. CAWI, DONALD T. SUMAD-ON
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Timing in trace conditioning of the nictitating membrane response of the rabbit (Oryctolagus cuniculus) : scalar, nonscalar, and adaptive features [PDF]
, 2010 Using interstimulus intervals (ISIs) of 125, 250, and 500 msec in trace conditioning of the rabbit nictitating membrane response, the offset times and durations of conditioned responses (CRs) were collected along with onset and peak latencies.
Richard S. Sutton +5 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Resolving and modeling the effects of Fe and Mn redox cycling on trace metal behaviour in a seasonally anoxic lake. [PDF]
, 2005 Vertical profiles of the dissolved and particulate (>0.45 μm) concentrations of Fe, Mn, Co, Ni, Cu, Pb, Al and Ba were determined on two occasions (14 and 22 August 1996) during summer stratification in a seasonally anoxic lake (Esthwaite Water, UK). The
Hamilton-Taylor, J. +7 more
core +1 more source
Trace Evidence from Mars’ Past: Fingerprinting Transverse Aeolian Ridges
Remote Sensing, 2019 Linear dunes and human fingerprints share many characteristics. Both have ridges, valleys, and defects (minutiae) in the form of bifurcations and termination of ridgeline features.
Louis Scuderi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source