Results 71 to 80 of about 376,028 (266)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A Novel LIBS Sensor for Sample Examinations on a Crime Scene
SensorsIn this work, we present a compact LIBS sensor developed for characterization of samples on a crime scene following requirements of law enforcement agencies involved in the project.
Violeta Lazic +7 more
doaj +1 more source
A Data-Driven Algorithm for Indoor/Outdoor Detection Based on Connection Traces in a LTE Network
IEEE Access, 2019 Environmental factors have a strong impact on the satisfaction of mobile users. Thus, estimating the context of a session is key to evaluating the end-user experience in mobile network management. Such a context is mainly defined by user location.
Juan L. Bejarano-Luque +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Potential of Integrated Video and Vehicle Forensic Investigation
Теория и практика судебной экспертизы, 2019 In some cases, the material provided for a forensic vehicle examination may be insufficient to answer the questions placed before the experts. However, sometimes there are some multimedia files presented which by means of forensic video examination can ...
S. S. Zharkikh +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The Ruin as Kairos in W. G. Sebald’s The Rings of Saturn
Études Britanniques Contemporaines, 2012 Beyond the obvious semiotic heterogeneity of linguistic signs and visual images, which accounts for the disruptive force of the inserted visual material in Sebald’s novel The Rings of Saturn, the text and image relation in this novel is a particular site
Anne-Laure Fortin-Tournès
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The conjugate trace and trace of a plane partition
Journal of Combinatorial Theory, Series A, 1973 AbstractThe conjugate trace and trace of a plane partition are defined, and the generating function for the number of plane partitions π of n with ⩽r rows and largest part ⩽m, with conjugate trace t (or trace t, when m = ∞), is found. Various properties of this generating function are studied.
openaire +1 more source