Results 191 to 200 of about 98,836 (311)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Induced Pluripotent Stem Cells as a Tool to Decipher the Normal and Abnormal Development of the Esophagus and Trachea from Normal Morphogenesis to Esophageal Atresia, Tracheomalacia, and Laryngo-Tracheal Clefts. [PDF]

Cells
Zhang Y, David A, Nemati A, Faure C.
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Complete tracheal transection at the thoracic inlet: successful reconstruction with intraoperative Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) support - case report. [PDF]

Int J Emerg Med
Luo H, Jiang L, Wang D.
europepmc   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Staged Endovascular and Surgical Management of Pediatric Tracheo-Innominate Artery Fistula: A Case Report. [PDF]

Ann Vasc Dis
Cao Y, Koide M, Yashima M, Sugiyama H, Nakashima Y, Matsushita A, Ishida K, Okui Y.   +7 more
europepmc   +1 more source

Receptor-mediated gene transfer to airway epithelial cells in primary culture [PDF]

, 1993
Agarwal, Santosh, Curiel, David T., Harris, C. E., Hu, P.-C., Wagner, Ernst   +4 more
core   +1 more source

Breaking through tradition: A new study on the 125I seeds implantation assisted by the puncture angle guidance device

Precision Medical Sciences, EarlyView.
This study showed the puncture angle guide device assisted 125I seeds implantation is safe and feasible. Compared with the manual deployment of needles, the puncture time, the number of puncture needle adjustments, and the number of intraoperative CT scans are significantly reduced, which can be used in clinical applications.
Yufeng Zhang, Yong Feng, Wenjie Guo, Xia He, Lele Zhang, Jiangping Yu, Xiuming Zhang, Wei Qiao   +7 more
wiley   +1 more source

ACOD1-itaconate in macrophage attenuates oxidative stress and inflammation in benign airway stenosis by upregulating and transferring FTH1. [PDF]

Redox Biol
Chen Y, Xu C, Luo T, Shi D, Guo X, Yang C, Dong Y, Huang H, Zhang Y, Zong Z, Wang X, Xu Z, Shi Y, Han C, Shi H, Bai C.   +15 more
europepmc   +1 more source

Leaf penetration by endophytic Metarhizium brunneum enables infection of Phthorimaea absoluta in tomato mines while inducing the crop defense system

Pest Management Science, EarlyView.
Spraying Metarhizium brunneum on tomato plants controls heterogeneous and upcoming Phthorimaea absoluta populations by infecting larvae within mines and priming plant induced systemic defences. Abstract BACKGROUND The endophytic entomopathogenic fungus Metarhizium brunneum Petch EAMa 01/58‐Su shows strong potential for managing Phthorimaea absoluta, a ...
Esther Aguilera Cuenca, María José García del Rosal, Fabián García Espinoza, Enrique Quesada Moraga, Irene Magdalena Rodríguez Gómez, Meelad Yousef Yousef   +5 more
wiley   +1 more source