Comparing the effect of using normal saline, N-acetyl cysteine and not using them in endotracheal tube suction on physiologic parameters and the amount of secretions in intubated patients under mechanical ventilation [PDF]
Aims: Today a large number of patients hospitalized in Intensive Care Unit need mechanical ventilation via an artificial air way. Since these patients have endotracheal tube, endotracheal suctioning is necessary for increasing oxygenation, cleaning the ...
Akbaryan Deheki, N. +6 more
core
[Surgical treatment of tracheal diseases].
The authors discuss different variants of resection of the trachea and adjacent organs in relation to the localization and character of the disease, the variants being used in 212 patients. Special attention is given to problems of plastic repair of the trachea defects after resection.
V P, Kharchenko +4 more
openaire +1 more source
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng +13 more
wiley +1 more source
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source
Background Idiopathic pulmonary arterial hypertension (IPAH) is a fatal illness. Despite many improvements in the treatment of these patients, there is no unique prognostic variable available to track these patients. The aim of this study was to evaluate
Majid Malekmohammad +8 more
doaj +1 more source
Experimental pneumonia induced by a Bordetella parapertussis-like organism in the ovine and murine lung : a thesis presented in partial fulfillment (70%) of the requirements for the degree of Master of Philosophy in Veterinary Pathology at Massey University [PDF]
Thirty-four specific pathogen-free (SPF) Swiss mice were intranasally inoculated with a suspension containing about 3 x 10 7 colony-forming units (CFU)/ml of a B. parapertussis-like organism isolated from pneumonic ovine lung.
Chen, Wangxue
core
Mechanical Instabilities of Biological Tubes
We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability.
A. P. Evan +9 more
core +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Smoking is known as a major cause of chronic obstructive pulmonary disease (COPD) and hence immediate and effective interventions are required for its elimination.
Mohammad Jamshidi Ardeshiri +5 more
doaj
Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis [PDF]
Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature.
Cellière, Géraldine +2 more
core +3 more sources

