Results 121 to 130 of about 401,308 (300)

High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis. [PDF]

, 2020
Mechanisms underpinning airway epithelial homeostatic maintenance and ways to prevent its dysregulation remain elusive. Herein, we identify that β-catenin phosphorylated at Y489 (p-β-cateninY489) emerges during human squamous lung cancer progression ...
Aros, Cody J, Bisht, Bharti, Chen, Michelle W, Damoiseaux, Robert, France, Bryan, Gomperts, Brigitte N, Meneses, Luisa K, Pantoja, Carla J, Paul, Manash K, Rickabaugh, Tammy M, Sandlin, Jenna M, Shia, David W, Tse, Jonathan A, Vijayaraj, Preethi   +13 more
core   +1 more source

Effects of chlorhexidine gluconate oral care on hospital mortality : a hospital-wide, observational cohort study [PDF]

, 2018
Chlorhexidine oral care is widely used in critically and non-critically ill hospitalized patients to maintain oral health. We investigated the effect of chlorhexidine oral care on mortality in a general hospitalized population.
Blot, Stijn, Deschepper, Mieke, Eeckloo, Kristof, Vogelaers, Dirk, Waegeman, Willem   +4 more
core   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Tracheal Collapse and Chronic Bronchitis as a Cause of Coughing in Dogs with Endocardiosis

Ветеринарная патология
Introduction. Chronic coughing in dogs of small breeds older than 8–10 years is a complex diagnostic and therapeutic problem. These dogs are often diagnosed with heart murmurs caused by mitral valve degeneration (endocardiosis), and many of them also ...
S. N. Kartashov, M. A. Petrova, A. I. Butenkov, A. S. Kartashova   +3 more
doaj   +1 more source

Endoscopic approach for a laryngeal neoplasm in a dog

Ciência Rural, 2015
Laryngeal and tracheal tumors are rare in pets; some piece of information on their disease behavior, therapy and evolution are limited. Neoplasms in this area are a diagnostic challenge.
Pedro Paulo Maia Teixeira, Erica Siqueira Souza, Paulo César Jark, Leandro Nassar Coutinho, Alanna do Socorro Lima da Silva, Marcos Vinicius Sicca Guiduce, Bruna Piva Maria, Paloma Espirito Santo Silva, Lívia Maria Souza Semolin, Marco Augusto Machado Silva, Wilter Ricardo Russiano Vicente, Mirela Tinucci-Costa, Andrigo Barboza De Nardi   +12 more
doaj   +1 more source

Clinical Outcomes in Patients With T4b Esophageal Squamous Cell Carcinoma: A 10‐Year Single Institution Experience

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) with adjacent structure invasion (T4b), affecting areas such as the aorta, vertebral body, or trachea, is associated with a poor prognosis, and the optimal treatment strategy remains unclear. While chemotherapy is considered standard, radiation therapy is often avoided due to the risk of severe ...
Yi‐Hsun Chen, Wen‐Hung Hsu, I‐Chen Wu, Pen‐Tzu Fang, Song‐Wei Wang, Chao‐Chin Hsu, Yao‐Kuang Wang   +6 more
wiley   +1 more source

Clinical and radiographic predictors of successful therapeutic bronchoscopy for the relief of malignant central airway obstruction

BMC Pulmonary Medicine, 2019
Background Malignant central airway obstruction (CAO) occurs in approximately 20–30% of patients with lung cancer and is associated with debilitating symptoms and poor prognosis.
Coral X. Giovacchini, Edward R. Kessler, Christopher M. Merrick, Junheng Gao, Xiaofei Wang, Momen M. Wahidi, Scott L. Shofer, George Z. Cheng, Kamran Mahmood   +8 more
doaj   +1 more source

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Health Risk Analysis of Heating Fuel Choice: Case Study in Kentucky [PDF]

Replaced with revised version of paper 02/03/09.Combustion-generated pollutants, indoor air pollution, heating fuel choice, health risk, Environmental Economics and Policy, Health Economics and Policy,
Liu, Zheng
core   +1 more source

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan, Rui Zhang, Yu‐er Li, Rui Li, Shao‐bo Ge, Jin Liu, Shi‐yuan Yao, Xia Yang, Tao Zhang, Ming Zhang   +9 more
wiley   +1 more source