Results 31 to 40 of about 66,008 (259)

Retrosternal Percutaneous Tracheostomy: An Approach for Predictably Impossible Classic Tracheostomy [PDF]

open access: yes, 2010
Percutaneous tracheostomy is a routine procedure in intensive care units. In cases of very low position of the larynx, cervical spine deformation, morbid obesity, or neck tumor, performance of the classic tracheostomy is inapplicable.
Eyal Raz   +7 more
core   +1 more source

531: EARLIER TRACHEOSTOMY DOES NOT IMPROVE OUTCOME IN STROKE PATIENTS: A META-REGRESSION ANALYSIS

open access: yes, 2023
Introduction: Stroke patients requiring mechanical ventilation (MV) often have poor prognosis. Early tracheostomy in critically ill patients purportedly reduces MV time and length of stay (LOS).
Palo Pelosi   +9 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

Timing of tracheostomy and hospital mortality in mechanically ventilated ICU patients: a prospective cohort study

open access: yesThe Egyptian Journal of Bronchology
Background The optimal timing of tracheostomy in mechanically ventilated critically ill patients remains controversial. Although early tracheostomy may reduce complications related to prolonged endotracheal intubation, its association with clinically ...
Mohammadhassan Keshavarz   +3 more
doaj   +1 more source

Assessing and enhancing pediatric residents’ knowledge and skills in tracheostomy care through simulation-based training

open access: yesFrontiers in Pediatrics
Background and ObjectivesThe pediatric residency program in Saudi Arabia currently does not include tracheostomy care as a competency. Research has indicated that nonsurgical residents have limited knowledge of tracheostomy management.
Hasan Ghandourah   +11 more
doaj   +1 more source

Effect of early tracheostomy in mechanically ventilated patients

open access: yesLaryngoscope Investigative Otolaryngology, 2019
Objective To investigate the effect of the timing of tracheostomy in patients who required prolonged mechanical ventilation using two methods: analysis of early versus late tracheostomy and landmark analysis.
Hirotomo Dochi   +4 more
doaj   +1 more source

Tracheostomy-related indications, early complications and their predictors among patients in low resource settings: a prospective cohort study in the pre-COVID-19 era

open access: yesBMC Surgery, 2023
Background Tracheostomy is a life-saving procedure whose outcomes may vary between hospitals based on disparities in their existing expertise. We aimed at establishing the indications, early tracheostomy-related complications and their associated factors
Daniel J. Nyanzi   +6 more
doaj   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

open access: yesAdvanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann   +7 more
wiley   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

open access: yesAdvanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin   +5 more
wiley   +1 more source

Impact of tracheostomy on clinical outcomes in ventilated patients with severe pneumonia: a propensity-matched cohort study [PDF]

open access: yesThe Korean Journal of Internal Medicine
Background/Aims Tracheostomy is a crucial intervention for severe pneumonia patients requiring prolonged mechanical ventilation (MV). However, debate persists regarding the influence of tracheostomy timing and performance on long-term survival outcomes ...
Hayoung Seong   +5 more
doaj   +1 more source

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