Results 41 to 50 of about 66,008 (259)

Indications and Outcomes of Tracheostomy in Children After Congenital Heart Surgery

Journal of Pediatric Emergency and Intensive Care Medicine, 2023
Introduction:In a minority of children after cardiovascular surgery may require prolonged mechanical ventilatory support and tracheostomy. We aim to describe indications, timing and, outcomes of the tracheostomy.Methods:A retrospective review of 12 ...
Pınar Yazıcı Özkaya, Eşe Eda Turanlı, İrem Ersayoğlu, Osman Nuri Tuncer, Bülent Karapınar   +4 more
doaj   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Clinical management and nursing care for patients with tracheostomy following traumatic brain injury

Frontiers in Neurology
Tracheostomy is a routine surgical procedure in patients with severe traumatic brain injury, which requires mechanical ventilation to maintain gas exchange and avoid hypoxemia. Inadequate tracheostomy timing, nursing care, and decannulation would lead to
Xiongyan Mao, Yuchan Zhou, Qiye Chen, Yelei Zhang   +3 more
doaj   +1 more source

Early vs. late tracheostomy for the ICU patients: Experience in a referral hospital

Saudi Journal of Anaesthesia, 2012
Objectives: The aim of this study is to present our experience with elective surgical tracheostomy for intensive care unit (ICU) patients who needed prolonged translaryngeal intubation in order to evaluate the proper timing and advantages of early vs ...
Tareq Mahafza, Sana Batarseh, Nader Bsoul, Ehab Massad, Ibraheem Qudaisat, Abd Elmon′em Al- Layla   +5 more
doaj   +1 more source

Milestone Attainment in Young Children With Arthrogryposis Multiplex Congenita: Developmental Profile and Associated Factors

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Evidence on developmental milestones in children with arthrogryposis multiplex congenita (AMC) under the age of five is scarce. This multisite cross‐sectional study described developmental status and examined factors associated with milestone attainment in 143 children aged 0–66 months from a pediatric AMC Registry.
Ahlam Zidan, Sophia C. Pasia, Emmanouil Rampakakis, Reggie Hamdy, Frank Rauch, Lauren C. Hyer, Joel Lerman, Haluk Altiok, Krister Freese, Cary Mielke, Sarah B. Nossov, Philip F. Giampietro, Thania Ordaz‐Robles, Noémi Dahan‐Oliel   +13 more
wiley   +1 more source

Early Versus Late Tracheostomy in Neurosurgical Intensive Care Patients Requiring Prolonged Mechanical Ventilation: A Prospective Observational Cohort Study

Bali Journal of Anesthesiology
Background: The optimal timing of tracheostomy in neurosurgical intensive care unit (ICU) patients remains uncertain. This study compared early- and late-tracheostomy groups in critically ill neurosurgical patients requiring prolonged mechanical ...
Aamir Hussain Hela, Zoya Sehar, Mohsin Fayaz   +2 more
doaj   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Percutaneous Dilatational Tracheostomy and Surgically Created Tracheostomy in ICU Patients [PDF]

, 2014
Introduction: Following advances of Intensive Care medicine and widespread administration of mechanical ventilation, tracheostomy has become one of the indispensable surgical procedures.
Samad EJ Golzari, Alireza Mahoori, Amir Mohammad Bazzazi, Tohid Karami, Mohammad Amin Valizade Hasanloei   +4 more
core   +1 more source

Acute toxic leucoencephalopathy following protonitazene ingestion

British Journal of Clinical Pharmacology, EarlyView.
Background Distribution of illicit counterfeit alprazolam containing the highly potent synthetic opioid‐receptor agonist protonitazene recently resulted in a number of severe overdoses in Ireland. We report three cases that presented to our hospital, within 6 weeks of one another, following ingestion of illicitly‐sourced alprazolam.
Ruadhan O'Laoi, Holly Acton, Pierce Kavanagh, Isabelle Hunt, Niall Sheehy, Cormac Kennedy   +5 more
wiley   +1 more source

Profession‐Related Accreditation Requirements in Australia Regarding Anatomy Teaching: A Web‐Based Desktop Audit

Clinical Anatomy, EarlyView.
ABSTRACT For effective and safe practice, health professionals need an understanding of functional anatomy. Registration boards, councils or self‐regulating professional associations determine the standards, codes, graduate competencies and education program accreditation requirements which inform health curricula development and content.
Anita Zacharias, Daniel J. English, Jennifer Selkirk‐Bell, Kelly Fielden, Bradley Halliday, Carol McKinstry   +5 more
wiley   +1 more source