Results 31 to 40 of about 314,401 (249)

Interactive Visualization of the Printed Circuits Tracing Algorithms for Educational Purposes

open access: yesЦифровая трансформация, 2023
A software module that allows interactive demonstration of maze routing algorithms for tracing printed conductors, which, during their operation, use a grid representation of a discrete working space of a printed circuit board has been developed.
D. O. Petrov
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A Framework for Detecting System Performance Anomalies Using Tracing Data Analysis

open access: yesEntropy, 2021
Advances in technology and computing power have led to the emergence of complex and large-scale software architectures in recent years. However, they are prone to performance anomalies due to various reasons, including software bugs, hardware failures ...
Iman Kohyarnejadfard   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

A Review on the Possibilities and Challenges of Today’s Soil and Soil Surface Assessment Techniques in the Context of Process-Based Soil Erosion Models

open access: yesRemote Sensing, 2022
To investigate relevant processes as well as to predict the possible impact of soil erosion, many soil erosion modelling tools have been developed. The most productive development of process-based models took place at the end of the 20th century.
Lea Epple   +5 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Contextualizing Holocaust Documents of the International Tracing Service (ITS) through an Interactive Online Guide

open access: yesQuest. Issues in Contemporary Jewish History, 2018
In 2018, the International Tracing Service (ITS) extends the online accessibility of further parts of its 30 million documents on the fate of Holocaust victims, of forced laborers and Displaced Persons.
Christiane Weber
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Take Note: the Effectiveness of Novice Programmers' Annotations on Examinations

open access: yesInformatics in Education, 2005
This paper examines results from a multiple-choice test given to novice programmers at twelve institutions, with specific focus on annotations made by students on their tests.
Robert MCCARTNEY   +3 more
doaj   +1 more source

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