Results 51 to 60 of about 1,184,573 (332)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Interactive Visualization of the Printed Circuits Tracing Algorithms for Educational Purposes

open access: yesЦифровая трансформация, 2023
A software module that allows interactive demonstration of maze routing algorithms for tracing printed conductors, which, during their operation, use a grid representation of a discrete working space of a printed circuit board has been developed.
D. O. Petrov
doaj   +1 more source

ROBAST: Development of a ROOT-Based Ray-Tracing Library for Cosmic-Ray Telescopes and its Applications in the Cherenkov Telescope Array

open access: yes, 2015
We have developed a non-sequential ray-tracing simulation library, ROOT-based simulator for ray tracing (ROBAST), which is aimed to be widely used in optical simulations of cosmic-ray (CR) and gamma-ray telescopes.
Noda, Koji   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Framework for Detecting System Performance Anomalies Using Tracing Data Analysis

open access: yesEntropy, 2021
Advances in technology and computing power have led to the emergence of complex and large-scale software architectures in recent years. However, they are prone to performance anomalies due to various reasons, including software bugs, hardware failures ...
Iman Kohyarnejadfard   +3 more
doaj   +1 more source

X-ray tracing using Geant4

open access: yes, 2008
We describe an extension to the Geant4 software package that allows it to be used as a general purpose X-ray tracing package. We demonstrate its use by building a model of the X-ray optics of the XMM-Newton, calculating its effective area, and comparing ...
Agostinelli   +8 more
core   +1 more source

Using schema transformation pathways for data lineage tracing [PDF]

open access: yes, 2005
With the increasing amount and diversity of information available on the Internet, there has been a huge growth in information systems that need to integrate data from distributed, heterogeneous data sources. Tracing the lineage of the integrated data is
A. Woodruff   +16 more
core   +4 more sources

Trace conditioning in insects—keep the trace! [PDF]

open access: yesFrontiers in Physiology, 2013
Trace conditioning is a form of associative learning that can be induced by presenting a conditioned stimulus (CS) and an unconditioned stimulus (US) following each other, but separated by a temporal gap. This gap distinguishes trace conditioning from classical delay conditioning, where the CS and US overlap.
Dylla, Kristina Verena   +3 more
openaire   +6 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy