Results 81 to 90 of about 1,124,915 (299)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Absence of COVID-19 workplace transmission from hairdressers in Victoria, Australia

open access: yesPublic Health Research & Practice, 2022
Ericka Swaney   +4 more
doaj   +1 more source

Supposed Corpses and Correspondence

open access: yesFree & Equal
The correspondence requirement is a fundamental doctrinal principle in Anglo-American criminal law.  It maintains that, in general, a particular relation between mens rea and actus reus is necessary for liability.
Elise Sugarman
doaj   +2 more sources

Fast Reliable Ray-tracing of Procedurally Defined Implicit Surfaces Using Revised Affine Arithmetic [PDF]

open access: yes, 2009
Fast and reliable rendering of implicit surfaces is an important area in the field of implicit modelling. Direct rendering, namely ray-tracing, is shown to be a suitable technique for obtaining good-quality visualisations of implicit surfaces. We present
Comninos, Peter   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Foodborne disease outbreaks in Jiangxi Province from 2012 to 2021

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo provide a scientific basis to establish further prevention and control strategies, the epidemiological characteristics of foodborne disease outbreaks from 2012 to 2021 in Jiangxi Province was analyzed.MethodsDescriptive analysis was conducted
ZENG Liai   +5 more
doaj   +1 more source

Field Monitoring With Delayed Saving

open access: yesIEEE Access, 2019
Field monitoring techniques can collect data about the behavior of software applications while running in the field, with real users and real data. Developers can exploit the information extracted from the field to timely improve, tune, and fix their ...
Oscar Cornejo   +4 more
doaj   +1 more source

Consumer Support for Food Tracing with RFID Technology [PDF]

open access: yes
Foodborne illness continues to be a significant problem and food traceability may help reduce the number and severity of outbreaks. One technology that could improve food tracing is radio frequency identification tags or RFID. However, some consumers may
Larson, Ronald B., Rana, Kulmani
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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