Results 51 to 60 of about 84,190 (259)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The Effectiveness of Complex Training to Develop Muscular Power in the Light of Genetic Diversity of Angiotensin-Converting Enzyme (ACE) on the Numerical Level in Triple Jump [PDF]

Assiut Journal of Sport Science and Arts, 2016
The researcher applied the experimental method for suiting the nature of the research by using the experimental layout of two experimental groups and conducting the pre and post-measurements.
Mohammed Mostafa Awad
doaj   +1 more source

Improving spatio-temporal stride parameters, lower limb muscles activity and race walkers’ records after 12-weeks special exercises using rhythmic auditory

Sport TK, 2023
This study aims to know the effect of 12-weeks of special exercises using rhythmic auditory to improve spatio-temporal stride parameters (STSP), lower limb muscles activity (LLMA), and 10000m racewalking time (RT).
Mohamed Megahed, Zahraa Tarek
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Postural control in top-level Para Karate athletes with visual and intellectual impairment: an observational study

BMC Sports Science, Medicine and Rehabilitation
Background Although the World Karate Federation (WKF) lacks a standardized test battery, Para Karate classification follows International Paralympic Committee (IPC) principles, with balance recognized as a key physical ability affecting kata performance.
Henrieta Horníková, Radovan Hadža, Michal Hrubý, Dušana Augustovičová   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Effect of a Training Program designed for the Improvement of Speed Endurance in Light of Genetic Diversity (ACE) on Some Signs of Muscle fatigue and on the Quantitative Level of the Runners of 1500m Run [PDF]

Assiut Journal of Sport Science and Arts, 2016
This research aimed at establishing a training program for the improvement of speed endurance in light of genetic diversity (ACE) for juniors in (1500m) run at the National Project for Talents at the governorate of Sharqia and identifying its effect on ...
Hossam Abou El-Maaty
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Intra-Set Velocity Decline and Set-to-Set Changes During a Standardized Moderate-Load Back Squat Protocol in Trained Track and Field Athletes

Applied Sciences
Velocity-based training (VBT) is widely used to monitor resistance training intensity and fatigue through movement velocity. However, repetition-by-repetition velocity behavior and set-to-set fatigue responses under standardized moderate-load conditions ...
Bumchul Chung
doaj   +1 more source