Results 61 to 70 of about 94,810 (281)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Sensors, 2020 This paper presents the investigation of the root causes of the fast degradation of a railway crossing. The dynamic performance of the crossing was assessed using the sensor-based crossing instrumentation, and the measurement results were verified using ...
Xiangming Liu, Valéri L. Markine
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Track ballast modelling by discrete element method
Građevinar, 2019 An increase in axle load and travel speed causes faster degradation of track structure and, hence, of the ballast prism. Crushing of stone grains in ballast due to excessive contact forces among these grains causes degradation in the form of filling of ...
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Minimising track degradation through managing vehicle/track interaction
, 2007 The rate at which a railway track deteriorates depends on the response of the track\ud \ud under different static and repeated dynamic forces. These wheel/rail forces lead to\ud \ud imperfections in the rail surface and deviation in track geometry ...
Hawari, Haitham M.
core
The influence of railway track components on track degradation
, 2023 Naloga obsega pregled elementov zgornjega ustroja železniške proge, meritve parametrov in analizo vpliva geometrijskih elementov na vrednosti parametrov. V prvem delu naloge je predstavljen potek degradacije zgornjega ustroja.
Ošep, Urška
core
Influence of Water Content on Track Degradation at Transition Zones
, 2022 This study aims to explore the role of water retention behaviour in the track degradation of the transition zone by examining the influence of water content variation.
Heitor, A, Zhu, F
core +1 more source