Results 111 to 120 of about 3,239,156 (327)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Hospital acquired drug resistant pathogens infections in patients with viral respiratory tract infections: a retrospective study

BMC Infectious Diseases
Background Viral respiratory infections (VRTIs) caused by influenza (Flu) and COVID-19 pose significant global health challenges. Clinical outcomes are further exacerbated by infections with hospital acquired drug resistant pathogens (DRPs).
Zibo Fan, Xinmin Xu, Qun Li, Tong Zhou, Aibin Wang, Chengjie Ma, Zhihai Chen, Lianhe Lu, Yuanyuan Zhang, Yajie Wang, Wei Zhang   +10 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Track 1 – Track 5 [PDF]

International Journal of Obesity, 2008
  +7 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Study on the Influence of Space–Time Adaptive Processor on Single Point Position and Real‐Time Kinematic for GNSS Antenna Array Anti‐jamming Receiver

IET Radar, Sonar & Navigation
Space‐time adaptive processor (STAP) has been widely used in the GNSS antenna array anti‐jamming receiver. The cost of STAP algorithms, including the minimum variance distortion‐less response (MVDR) algorithm and power inversion (PI) algorithm, is ...
Yaoding Wang, Xiaozhou Ye, Si Chen, Zhenxin Liu   +3 more
doaj   +1 more source

دراسة تحلیلیة لمستوى اتساق محتوى کتب الفقه وأصوله للمسارین المشترک والإنسانی فی المرحلة الثانویة فی المملکة العربیة السعودیة مع المعاییر الوطنیة لمجال تعلم التربیة الإسلامیة. Analytical Study for the Level of Alignment of Jurisprudence and its Foundations in the Two Tracks of High School: Common and Humanity in the KSA with the National Strandards [PDF]

, 2020
بندر بن محمد المطری
openalex   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Lower immune senescence of T cell subsets among virologically suppressed Chinese men who have sex with men living with HIV in comparison with those ART naive

BMC Infectious Diseases
Background Immune senescence can occur in untreated HIV infection and is partially reversible with effective antiretroviral therapy (ART). Here, we investigated the differences in immune senescence of T cell subsets among Chinese men who have sex with ...
Li Li, Fengting Yu, Siyuan Yang, Hui Li, Yunxia Tang, Chengjie Ma   +5 more
doaj   +1 more source