Results 71 to 80 of about 3,239,156 (327)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Efficiently Tracking Homogeneous Regions in Multichannel Images
, 2017 We present a method for tracking Maximally Stable Homogeneous Regions (MSHR) in images with an arbitrary number of channels. MSHR are conceptionally very similar to Maximally Stable Extremal Regions (MSER) and Maximally Stable Color Regions (MSCR), but ...
Böttger, Tobias, Eisenhofer, Christina
core +1 more source
Calculating track thrust with track functions [PDF]
Physical Review D, 2013 In e+e- event shapes studies at LEP, two different measurements were sometimes performed: a "calorimetric" measurement using both charged and neutral particles, and a "track-based" measurement using just charged particles. Whereas calorimetric measurements are infrared and collinear safe and therefore calculable in perturbative QCD, track-based ...
Chang, Hsi-Ming +3 more
openaire +3 more sources
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Unambiguous Tracking Method Based on Combined Correlation Functions for sine/cosine-BOC CBOC and AltBOC Modulated Signals [PDF]
, 2014 Unambiguous tracking for Binary Offset Carrier (BOC) modulated signals is an important requirement of modern Global Navigation Satellite System (GNSS) receivers.
Jia, W.M. +3 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Radar Constant-Modulus Waveform Design with Prior Information of the Extended Target and Clutter
Sensors, 2016 Radar waveform design is of great importance for radar system performances and has drawn considerable attention recently. Constant modulus is an important waveform design consideration, both from the point of view of hardware realization and to allow for
Wenzhen Yue +3 more
doaj +1 more source
Australian and International Journal of Rural Education, 2014 Previous research related to this study explored early career female leaders’ experiences in rural school settings, and probed the personal and professional challenges they faced and their motivations to accept formal and informal leadership roles ahead of the usual timeframes (e.g., Graham, Miller & Paterson, 2009).
Judith Miller +2 more
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source