Results 71 to 80 of about 1,519,271 (256)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A Cost-Effective Tracking Algorithm for Hypersonic Glide Vehicle Maneuver Based on Modified Aerodynamic Model

Applied Sciences, 2016
In order to defend the hypersonic glide vehicle (HGV), a cost-effective single-model tracking algorithm using Cubature Kalman filter (CKF) is proposed in this paper based on modified aerodynamic model (MAM) as process equation and radar measurement model
Yu Fan, Wuxuan Zhu, Guangzhou Bai
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Tracking MEP installation works [PDF]

, 2013
Recent research efforts to improve construction progress tracking has focused on employing emerging technologies such as three dimensional (3D) imaging, including digital photogrammetry and 3D Terrestrial Laser Scanning (TLS). Previous research has shown
Chiamone, Tiziana, Ciribini, Angelo, F. Bosché, Haas, Carl T., T. Chiamone, Bosché, Frédéric, Vassena, Giorgio, Y. Turkan, Turkan, Yelda, C.T. Haas, G. Vassena, A. Ciribini, CIRIBINI, Angelo Luigi Camillo, Bosche F., Chiamone T., Turkan Y., VASSENA, Giorgio Paolo Maria, Yelda, Turkan, Frederic, Nicolas Boschè, Haas C. T., Ciribini A., Vassena G., Carl, Haas   +22 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Habitat and movement selection processes of American lobster/jakej within a restricted bay in the Bras d’Or Lake/Pitu’paq, Nova Scotia, Canada

Movement Ecology
American lobster inhabit the unique, brackish Bras d’Or Lake system, although densities are low compared to areas with similar habitats in the Atlantic Ocean.
Shannon Landovskis, Megan Bailey, Sara Iverson, Skyler Jeddore, Robert J. Lennox, Caelin Murray, Fred Whoriskey   +6 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Two-component system GrpP/GrpQ promotes pathogenicity of uropathogenic Escherichia coli CFT073 by upregulating type 1 fimbria

Nature Communications
Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infections (UTIs). Invasion into bladder epithelial cells (BECs) on the bladder luminal surface via type 1 fimbria is the first critical step in UPEC infection.
Xueping Li, Yu Pang, Lingyan Jiang, Le Liu, Jiarui Zhou, Chen Jin, Qian Wang, Hongmin Sun, Qing Li, Zhen Chen, Jingliang Qin, Jianwei Mu, Bin Liu, Qiyue Zhang, Yutao Liu, Lu Feng, Lei Wang   +16 more
doaj   +1 more source

Real-time multiple object tracking using virtual shells [PDF]

, 2013
This paper presents a new multiple object tracking framework where arbitrarily shaped complex objects having severe occlusions are successfully tracked in real-time using stationary cameras.
Erdoğan, Hakan, Kekeç, İbrahim Taygun, Ünel, Mustafa, Taygun Kekec, Hakan Erdogan, Mustafa Unel   +5 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source