Results 71 to 80 of about 696,988 (267)

Hospital acquired drug resistant pathogens infections in patients with viral respiratory tract infections: a retrospective study

BMC Infectious Diseases
Background Viral respiratory infections (VRTIs) caused by influenza (Flu) and COVID-19 pose significant global health challenges. Clinical outcomes are further exacerbated by infections with hospital acquired drug resistant pathogens (DRPs).
Zibo Fan, Xinmin Xu, Qun Li, Tong Zhou, Aibin Wang, Chengjie Ma, Zhihai Chen, Lianhe Lu, Yuanyuan Zhang, Yajie Wang, Wei Zhang   +10 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Blind Direction-of-Arrival Estimation with Uniform Circular Array in Presence of Mutual Coupling

International Journal of Antennas and Propagation, 2016
A blind direction-of-arrival (DOA) estimation algorithm based on the estimation of signal parameters via rotational invariance techniques (ESPRIT) is proposed for a uniform circular array (UCA) when strong electromagnetic mutual coupling is present ...
Song Liu, Lisheng Yang, Shizhong Yang, Qingping Jiang, Haowei Wu   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

BNP-Track: a framework for superresolved tracking

Nature Methods
Abstract Superresolution tools, such as PALM and STORM, provide nanoscale localization accuracy by relying on rare photophysical events, limiting these methods to static samples. By contrast, here, we extend superresolution to dynamics without relying on photodynamics by simultaneously determining emitter numbers and their tracks ...
Ioannis Sgouralis, Lance W. Q. Xu, Ameya P. Jalihal, Zeliha Kilic, Nils G. Walter, Steve Pressé   +5 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Study on the Influence of Space–Time Adaptive Processor on Single Point Position and Real‐Time Kinematic for GNSS Antenna Array Anti‐jamming Receiver

IET Radar, Sonar & Navigation
Space‐time adaptive processor (STAP) has been widely used in the GNSS antenna array anti‐jamming receiver. The cost of STAP algorithms, including the minimum variance distortion‐less response (MVDR) algorithm and power inversion (PI) algorithm, is ...
Yaoding Wang, Xiaozhou Ye, Si Chen, Zhenxin Liu   +3 more
doaj   +1 more source

An Assessment Method for Ability Increment of Scientific Researchers Based on Interval Evaluation and Cloud Model Theory

Mathematics
The evaluation of the ability increment of scientific researchers is the most direct method to test the effect of scientific research training. Considering the variety and high professionalism of scientific research positions, and in order to reduce the ...
Hong Yang, Si Chen, Zhengrong Wu, Wenzhe Ding   +3 more
doaj   +1 more source