Results 91 to 100 of about 2,413,550 (311)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Urban Deployment Model: A Toolset for the Simulation and Performance Characterization of Radiation Detector Deployments in Urban Environments

Sensors
Static and mobile radiation detectors can be deployed in urban environments for a range of nuclear security applications, including radiological source search-and-tracking scenarios.
Nicolas Abgrall, Yassid Ayyad, Chun Ho Chow, Reynold Cooper, Daniel Hellfeld, Emil Rofors   +5 more
doaj   +1 more source

Data-Fusion for a Vision-Aided Radiological Detection System: Sensor dependence and Source Tracking

EPJ Web of Conferences, 2018
The University of Florida is taking a multidisciplinary approach to fuse the data between 3D vision sensors and radiological sensors in hopes of creating a system capable of not only detecting the presence of a radiological threat, but also tracking it ...
Stadnikia Kelsey, Martin Allan, Henderson Kristofer, Koppal Sanjeev, Enqvist Andreas   +4 more
doaj   +1 more source

Fabrication of low-cost, large-area prototype Si(Li) detectors for the GAPS experiment

, 2018
A Si(Li) detector fabrication procedure has been developed with the aim of satisfying the unique requirements of the GAPS (General Antiparticle Spectrometer) experiment. Si(Li) detectors are particularly well-suited to the GAPS detection scheme, in which
Aramaki, Tsuguo, Carr, Rachel, Erjavec, Tyler, Fuke, Hideyuki, Garvin, Amani, Hailey, Charles J., Harper, Cassia, Kewley, Glenn, Madden, Norman, Mechbal, Sarah, Perez, Kerstin, Rogers, Field, Saffold, Nathan, Tajiri, Gordon, Tokuda, Katsuhiko, Williams, Jason, Yamada, Minoru   +16 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Online Domain Adaptation for Multi-Object Tracking

, 2015
Automatically detecting, labeling, and tracking objects in videos depends first and foremost on accurate category-level object detectors. These might, however, not always be available in practice, as acquiring high-quality large scale labeled training ...
Gaidon, Adrien, Vig, Eleonora
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Dosimetric precision of an ion beam tracking system

Radiation Oncology, 2010
Background Scanned ion beam therapy of intra-fractionally moving tumors requires motion mitigation. GSI proposed beam tracking and performed several experimental studies to analyse the dosimetric precision of the system for scanned carbon beams.
Kraft Gerhard, Durante Marco, Schardt Dieter, Chaudhri Naved, Saito Nami, Gemmel Alexander, Bert Christoph, Rietzel Eike   +7 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Multiple Object Tracking in Urban Traffic Scenes with a Multiclass Object Detector

, 2018
Multiple object tracking (MOT) in urban traffic aims to produce the trajectories of the different road users that move across the field of view with different directions and speeds and that can have varying appearances and sizes.
B Coifman, HW Kuhn, J-P Jodoin, K Bernardin, Luis M. Fuentes, PF Felzenszwalb, RE Kalman, S Aslani   +7 more
core   +1 more source