Results 41 to 50 of about 6,438,052 (326)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

The Structural Framework and Opening Appearance of the VP1-Pocket of Enteroviruses Correlated with Viral Thermostability

open access: yesPathogens
Enteroviruses (EVs and RVs) are prevalent worldwide and cause various diseases in humans, of which the VP1-pocket is a target of antivirals, with a lipid molecule as a pocket factor to stabilize the virion.
Xiaojing Lin   +7 more
doaj   +1 more source

Eye-tracking data and mathematical tasks with focus on mathematical reasoning

open access: yesData in Brief, 2019
This data article contains eye-tracking data (i.e., dwell time and fixations), Z-transformed cognitive data (i.e., Raven's Advanced Progressive Matrices and Operation span), and practice and test scores from a study in mathematics education. This data is
Mathias Norqvist   +2 more
doaj   +1 more source

Antimicrobial Stewardship Practices of Community Pharmacists in United Arab Emirates

open access: yesAntibiotics, 2023
Background: The purpose of this paper is to assess the implementation of antimicrobial stewardship (AMS) activities in community pharmacies in the United Arab Emirates (UAE).
Mohammad M. AlAhmad   +5 more
doaj   +1 more source

Expectations on Track? High School Tracking and Adolescent Educational Expectations [PDF]

open access: yesSocial Forces, 2015
This paper examines the role of adaptation in expectation formation processes by analyzing how educational tracking in high schools affects adolescents’ educational expectations. I argue that adolescents view track placement as a signal about their academic abilities and respond to it in terms of modifying their educational expectations.
openaire   +3 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

A Novel Peptide from VP1 of EV-D68 Exhibits Broad-Spectrum Antiviral Activity Against Human Enteroviruses

open access: yesBiomolecules
Enteroviruses have been a historical concern since the identification of polioviruses in humans. Wild polioviruses have almost been eliminated, while multiple species of non-polio enteroviruses and their variants co-circulate annually.
Xiaojing Lin   +9 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Understanding Issues Associated with Tracking Students in Mathematics Education

open access: yesJME (Journal of Mathematics Education), 2018
Academic tracking, particularly in subjects like mathematics, has existed in the United States’ education system for decades. A problem with tracking is that, in many cases, students are sorted based on external factors beyond their control, rather than ...

semanticscholar   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

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