Results 141 to 150 of about 293,620 (283)

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

Advanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki, Yoshitaka Koseki, Kunikazu Ishii, Minsang Kim, Keita Tanita, Kota Sato, Toru Nakazawa, Satoshi Katsube, Daisuke Unabara, Tasuku Hamaguchi, Keisuke Kawakami, Koji Yonekura, Akihide Hibara, Atsushi Wakamiya, Hiroshi Uji‐I, Hitoshi Kasai   +18 more
wiley   +1 more source

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

Advanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu, Jingfan Wang, Pengfei Ge, Qinyuan Gu, Hongying Li, Yuanyuan Fan, Haiyue Xie, Yangyang Lu, Yifan Lin, Xinjing Wu, Chengkun Wang, Ping Xie, Zizhong Hu   +12 more
wiley   +1 more source

Are there age limitations for skull traction? Gardner-Wells tongs as a salvage measure in a 6-week-old infant with C3 cervical spinal cord compression: illustrative case. [PDF]

J Neurosurg Case Lessons
Al-Abri AM, Al-Ghaithi A, Attalah M, Al Farii H.   +3 more
europepmc   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Intraoperative traction in posterior spinal fusion for adolescent idiopathic scoliosis: an updated systematic review and meta-analysis of correction, perioperative, and safety outcomes. [PDF]

Front Pediatr
Tang Q, Xu R, Zhang L, Liu H, Wang W.
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Clinical Outcomes of Rubber-clip-assisted Versus Conventional Colorectal Endoscopic Submucosal Dissection: A Retrospective Study. [PDF]

DEN Open
Uyama K, Iwagami H, Akamatsu T, Sakano R, Kitada T, Shimoyama M, Terashita T, Nakatani Y, Uenoyama Y, Yamashita Y.   +9 more
europepmc   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source