Results 41 to 50 of about 173,626 (269)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Effect of Control Measures on Wheel/Rail Noise When the Vehicle Curves

open access: yesApplied Sciences, 2017
This paper developed a time domain simplified model to study the effect of control measures on wheel/rail noise when the vehicle curves. The time domain model consists of two parts, one being a vehicle-track coupling dynamic model for wheel/rail ...
Jian Han   +5 more
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

Calculation of Nonlinear Stiffness of Rubber Pad under Different Temperatures and Prepressures

open access: yesShock and Vibration, 2020
The static stiffness of rubber springs is affected by temperature and prepressure. In this thesis, the relationship between Young’s modulus and temperature of rubber was studied, and the quantitative relationship between them was determined.
Chuanbo Xu   +3 more
doaj   +1 more source

Research on the Influence of Wheel Polygonization on Axle Stress

open access: yesShock and Vibration, 2021
To study the influence of wheel polygonization on the dynamic stress of the wheel axle, a vehicle-track rigid-flexible coupling dynamic model was established.
Fubing Zhang   +4 more
doaj   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

A dynamic simulation of the wheel–rail impact caused by a wheel flat using a 3-D rolling contact model

open access: yesJournal of Modern Transportation, 2017
A three-dimensional (3-D) wheel-rail rolling contact model with a wheel flat was built using commercial software Hypermesh, and the dynamic finite element simulation was conducted using LS-DYNA 3D/explicit code. Influences of the train speed, flat length
Liangliang Han, Lin Jing, Kai Liu
doaj   +1 more source

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

open access: yesAdvanced Healthcare Materials, EarlyView.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko   +8 more
wiley   +1 more source

Experimental Study and Life Prediction of Bolt Loosening Life under Variable Amplitude Vibration

open access: yesShock and Vibration, 2019
The transverse vibration test of bolts has been designed with adoption of the fatigue tester to study the features of the loosening life of bolts. Firstly, the transverse vibration frequency has been changed, the effects of the amplitudes of displacement,
Guangwu Yang   +5 more
doaj   +1 more source

A Fault Diagnosis Method of Bogie Axle Box Bearing Based on Spectrum Whitening Demodulation

open access: yesSensors, 2020
The axle box bearing of bogie is one of the key components of the rail transit train, which can ensure the rotary motion of wheelsets and make the wheelsets adapt to the conditions of uneven railways.
Zejun Zheng   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy