Results 71 to 80 of about 1,149,451 (336)

Radar-Centric ISAC Through Index Modulation: Over-the-air Experimentation and Trade-offs [PDF]

open access: green, 2023
Murat Temiz   +4 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Urbanization Intensified the Trade‐Off Between Food Security and Water Quality Security in the Yangtze River Delta

open access: yesEarth's Future
Rapid urbanization, while enhancing the living standards, posed significant challenges to food security (FS) and water quality security (WQS). Previous research mainly focused on assessing FS and WQS, remaining their trade‐off and driving pathway unclear.
Fei Xue   +5 more
doaj   +1 more source

Samuelson and Solow on the Phillips Curve and the “Menu of Choice”: A Retrospective

open access: yesŒconomia, 2013
This paper focuses on the seminal contribution to the Phillips curve discussion by Samuelson and Solow in 1960, which is usually considered as the first trade-off interpretation of the Phillips curve.
Johannes A. Schwarzer
doaj   +1 more source

A poverty-inequality trade-off? [PDF]

open access: yes
The idea that developing countries face a trade-off between poverty and inequality has had considerable influence on thinking about development policy. The experience of developing countries in the 1990s does not, however, reveal any sign of a systematic
Ravallion, Martin
core  

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Taboos and conflicts in decision making [PDF]

open access: yesJudgment and Decision Making, 2008
Previous studies suggest that choices are perceived as difficult as well as negatively emotion-laden when they tap into moral considerations. However, we propose that the involvement of moral issues and values can also facilitate decisions because people
Martin Hanselmann, Carmen Tanner
doaj  

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

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