Results 31 to 40 of about 1,946,147 (307)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

ASEAN-New Zealand trade relations and trade potential [PDF]

open access: yes, 2010
This paper explores trade development by the Association of South East Asian Nations (ASEAN) with a particular reference to New Zealand and in the context of free trade agreements and partnerships. It describes the history of ASEAN, its trade composition,
Bano, Sayeeda
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Participation in International Integration Associations as a Factor of Ukraine’s Global Competitive Power

open access: yesStudia Regionalne i Lokalne, 2023
Current glocalisation processes require the identification of priority areas for Ukraine’s further integration into the international economy. The right choice of direction, tools and forms of implementation allows the government to determine, justify ...
Olena Zayats   +4 more
doaj   +1 more source

Regulatory Negotiations and Other Rulemaking Processes: Strengths and Weaknesses from an Industry Viewpoint [PDF]

open access: yes, 1997
In this Article, the author will describe some of the American Petroleum Institute\u27s experiences in recent EPA rulemaking processes, principally rulemakings conducted pursuant to the Clean Air Act.
Siegler, Ellen
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Are trade and transport logistics activities mutually reinforcing? Some empirical evidences from ASEAN countries

open access: yesJournal of Shipping and Trade, 2019
Both trade and transport logistics activities have impressively flourished among the Association of Southeast Asian Nations (ASEAN) countries over the past decades.
Kee-hung Lai   +4 more
doaj   +1 more source

Is organic food healthier? International research association FQH intensifies research. [PDF]

open access: yes, 2004
The paper gives a brief overview of the activities of the Organic Food Quality and Health Research Association - Organic FQH. The FQH Association encourages, co-ordinates and disseminates research in the field of organic food and health. Offically
Hooijdonk, van, Marijke
core  

Modern Integrated Associations: Comparative Analysis of Economic Growth Factors [PDF]

open access: yes, 2015
In the article, the results of the research, which purpose is to ground and assess the factors of economic growth of regional integration communities and national economies of member countries that develop them, are presented.
Doroshenko, S. V.   +2 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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