Results 41 to 50 of about 1,757,706 (300)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The trade-GDP ratio as a measure of openness [PDF]

open access: yes, 2023
The ratio of trade to GDP is often used as a summary measure of a country's openness to the rest of the world. It is well known that the trade-GDP ratio is affected by relatively time-invariant factors, such as country size and remoteness from trading ...
Tian, Mo   +3 more
core   +1 more source

Has China-ASEAN Trade opening increased China’s carbon emissions?

open access: yesChinese Journal of Population, Resources and Environment, 2023
This study uses carbon emission data at the provincial level in China between 1998–2018 and the proportion of the total import and export trade between provinces and the Association of Southeast Asian Nations (ASEAN) in GDP to measure the level of China ...
Yanchun Yi, Yixin Geng, Mingxin Yang
doaj   +1 more source

BEYOND CONVENTIONAL TRADE: TRADE OPENNESS IMPLICATIONS OF TRADE IN VALUE ADDED

open access: yesThe Singapore Economic Review, 2020
This study compares the impacts of gross trade openness measures with trade openness in value-added measures on economic growth for the years 1995–2014 by employing a dynamic panel data estimation. Our findings suggest that although gross trade shares promote growth, using value-added trade shares magnifies this positive effect.
HALIT YANIKKAYA, ABDULLAH ALTUN
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

On the asymmetric effects of trade openness on CO2 emissions in SADC with a nonlinear ARDL approach

open access: yesDiscover Sustainability, 2023
In this study, the expected asymmetric relationship between trade openness and CO2 emissions is investigated for the Southern African Development Community (SADC).
Maxwell Chukwudi Udeagha   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Drivers of trade market behavior effect on renewable energy consumption: a study of MINT (Mexico, Indonesia, Nigeria, and Turkey) economies

open access: yesDiscover Sustainability
This study provides an in-depth analysis of how key macro trade determinants affect renewable energy consumption in MINT economies (Mexico, Indonesia, Nigeria, and Turkey) over the period from 1995 to 2022.
Shahida Suleman   +6 more
doaj   +1 more source

The nexus between economic growth, financial development, trade openness, and CO2 emissions in European countries

open access: yesCogent Economics & Finance, 2017
In this paper, we empirically investigate the causal nexus between economic growth (GDP), CO2 emissions (environmental degradation), financial development, and trade openness using the ordinary least squares technique for a yearly panel data of 40 ...
Lamia Jamel, Samir Maktouf
doaj   +1 more source

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