Results 41 to 50 of about 12,677 (262)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Has China-ASEAN Trade opening increased China’s carbon emissions?

open access: yesChinese Journal of Population, Resources and Environment, 2023
This study uses carbon emission data at the provincial level in China between 1998–2018 and the proportion of the total import and export trade between provinces and the Association of Southeast Asian Nations (ASEAN) in GDP to measure the level of China ...
Yanchun Yi, Yixin Geng, Mingxin Yang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On the asymmetric effects of trade openness on CO2 emissions in SADC with a nonlinear ARDL approach

open access: yesDiscover Sustainability, 2023
In this study, the expected asymmetric relationship between trade openness and CO2 emissions is investigated for the Southern African Development Community (SADC).
Maxwell Chukwudi Udeagha   +1 more
doaj   +1 more source

Openness, Government Size and the Terms of Trade [PDF]

open access: yesReview of Economic Studies, 2008
This paper investigates the relationship between trade openness and the size ofngovernments, both theoretically and empirically. We argue that openness can increase the size of governments through two channels: (1) a terms of trade externality, whereby trade lowers the domestic cost of taxation, and (2) the demand for insurance, whereby trade raises ...
EPIFANI, PAOLO, G. Gancia
openaire   +7 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The nexus between economic growth, financial development, trade openness, and CO2 emissions in European countries

open access: yesCogent Economics & Finance, 2017
In this paper, we empirically investigate the causal nexus between economic growth (GDP), CO2 emissions (environmental degradation), financial development, and trade openness using the ordinary least squares technique for a yearly panel data of 40 ...
Lamia Jamel, Samir Maktouf
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

DAMPAK KETERBUKAAN PERDAGANGAN INTERNASIONAL SEKTOR JASA TERHADAP PERTUMBUHAN EKONOMI: PENDEKATAN PANEL DINAMIS

open access: yesJurnal Ekonomi dan Bisnis Airlangga, 2017
Trade liberalization led the economy around the world becomes increasingly open to both trade in goods and trade in services. This study aims to analyze the impact of openness trade in services on economic growth.
Faizatul Amala, Unggul Heriqbaldi
doaj   +1 more source

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