Results 41 to 50 of about 12,520 (262)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
On the asymmetric effects of trade openness on CO2 emissions in SADC with a nonlinear ARDL approach
Discover Sustainability, 2023 In this study, the expected asymmetric relationship between trade openness and CO2 emissions is investigated for the Southern African Development Community (SADC).
Maxwell Chukwudi Udeagha +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Jurnal Ekonomi dan Bisnis Airlangga, 2017 Trade liberalization led the economy around the world becomes increasingly open to both trade in goods and trade in services. This study aims to analyze the impact of openness trade in services on economic growth.
Faizatul Amala, Unggul Heriqbaldi
doaj +1 more source
Has China-ASEAN Trade opening increased China’s carbon emissions?
Chinese Journal of Population, Resources and Environment, 2023 This study uses carbon emission data at the provincial level in China between 1998–2018 and the proportion of the total import and export trade between provinces and the Association of Southeast Asian Nations (ASEAN) in GDP to measure the level of China ...
Yanchun Yi, Yixin Geng, Mingxin Yang
doaj +1 more source
Trade, Trade Openness and Macroeconomic Performance
Procedia - Social and Behavioral Sciences, 2016 AbstractThe paper examines the link between trade, trade openness and macroeconomic performance. The main methods used in the paper are a descriptive and comparative analysis of significant empirical studies during the past decades. Based on the presented literature, the empirical results indicate a positive effect of trade and trade openness on ...
openaire +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Openness, Government Size and the Terms of Trade [PDF]
Review of Economic Studies, 2008 This paper investigates the relationship between trade openness and the size ofngovernments, both theoretically and empirically. We argue that openness can increase the size of governments through two channels: (1) a terms of trade externality, whereby trade lowers the domestic cost of taxation, and (2) the demand for insurance, whereby trade raises ...
EPIFANI, PAOLO, G. Gancia
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source