Results 51 to 60 of about 12,677 (262)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Trade Openness and the Growth–Poverty Nexus: A Reappraisal with a New Openness Indicator

Asian Development Review
Developing countries have greatly benefited from globalization, coinciding with economic growth and structural transformation. The standard trade theory postulates that trade openness contributes to poverty alleviation directly by changing factor ...
WANNAPHONG DURONGKAVEROJ
doaj   +1 more source

Trade Openness, Economic Growth and Convergence: Evidence from Selected Asian Countries

Malaysian Management Journal, 2020
It is argued that countries, which adopt an open economic policy, enjoy faster economic growth than countries which do not, suggesting that "trade openness" can spur economic growth.
Mohd Zaini Abdul Karim
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Drivers of trade market behavior effect on renewable energy consumption: a study of MINT (Mexico, Indonesia, Nigeria, and Turkey) economies

Discover Sustainability
This study provides an in-depth analysis of how key macro trade determinants affect renewable energy consumption in MINT economies (Mexico, Indonesia, Nigeria, and Turkey) over the period from 1995 to 2022.
Shahida Suleman, Farrukh Nawaz, Umar Kayani, Ahmet Faruk Aysan, Mariam Sohail, Hassanudin Mohd Thas Thaker, Syed Arslan Haider   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Openness and Output Volatility in Sub-Saharan African Countries: Does Economic Freedom Matter?

JDE (Journal of Developing Economies)
Objective: The role of financial and trade openness in output volatility has been widely debated, while the moderating role of economic freedom remains underexplored.
Dagim Tadesse Bekele, Adisu Abebaw Degu
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Effect of Trade Surplus on External Debt in Developing Countries: Evidence from General-to-Specific Model

Gadjah Mada International Journal of Business
This paper examines the impact of trade openness towards external debt levels in low- and middle-income countries from 1980-2021. Using panel estimation of Fixed Effects (FE) and the General-to-Specific (GETS), the researchers segregated into Model 1 and
Abdul Aziz Karia, Taufik Abd Hakim
doaj   +1 more source