Results 41 to 50 of about 2,609,350 (310)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The impact of BRICS trade facilitation on China’s import and export trade in agricultural products

open access: yesFrontiers in Sustainable Food Systems
Trade facilitation is essential for enhancing the import and export of agricultural products between China and BRICS countries. Improving trade efficiency and identifying potential opportunities contribute to establishing formal cooperation mechanisms ...
Gao Xin, Humayun Khan, Xin Ling
doaj   +1 more source

A Study on Iran's Opportunities for Trade Integration with Central Asian Countries [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2013
Due to increasing economic globalization and the need for greater global participation of countries, policy-makers and politicians throughout the world have broadly addressed the regional cooperation in the past two decades.
Behzad Doulati, Shukurov Buri Urakovich
doaj  

Evaluation of the export potential of Latvia with EU countries categorized by groups of goods

open access: yesForum Scientiae Oeconomia, 2018
The relevance of the research subject is related to the fact that exports are an integral part of the overall economic potential of any state and largely determine the pace of its economic development.
Erica Pancenko, Tatyana Ivanova
doaj   +1 more source

Innovative potential of trade enterprises

open access: yesEconomics. Finances. Law, 2020
Our trends, formed in the conditions of active development of the post-industrial economy, dictate the need to apply an innovative approach not only to the development of the manufacturing sector, but also to form the innovative potential of service enterprises, which include trade enterprises.
Oksana KRAVCHENKO, Nataliia MASHOSHYNA
openaire   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Turning Crisis into Opportunity: Unfolding Ukraine’s Trade Potential with the Canada-Ukraine Free Trade Agreement

open access: yesEast/West: Journal of Ukrainian Studies, 2021
To offset the devastating effects of the trade war waged by the Russian Federation, Ukraine has undertaken laudable efforts since 2014 to negotiate new trade agreements with other states.
Iryna Bogdanova
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The Hidden Costs of Trade: Institutional and Cultural Determinants of Export Efficiency for Vietnam’s Wood Products

open access: yesEconomies
Vietnam’s wooden forest products industry is an important export sector, contributing to industrial growth and employment. However, it is facing increasing pressures related to challenges such as forest and export sustainability.
Phong Nguyen   +2 more
doaj   +1 more source

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