Results 41 to 50 of about 10,316,048 (305)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

An empirical analysis of Pakistan’s bilateral trade and trade potential with China: A gravity model approach

Cogent Economics & Finance, 2018
The decades-long history of friendly relationship in both countries bore the fruits in the form of Pakistan–China free-trade agreement (PCFTA) in 2006. This paper aims to estimate Pakistan’s bilateral trade potential with China by employing gravity model
Muhammad Saqib Irshad, Qi Xin, Zhang Hui, Hamza Arshad   +3 more
doaj   +1 more source

Potential risk of regional disease spread in west Africa through cross-border cattle trade [PDF]

, 2013
Transboundary animal movements facilitate the spread of pathogens across large distances. Cross-border cattle trade is of economic and cultural importance in West Africa.
Bassirou Bonfoh, Dean, A S, Fournié, G, Basel, G. Aboudou Boukaya (444126), Schelling Esther, Kulo Abalo E., Boukaya G. Aboudou, Kulo, Abalo E., Anna S. Dean (113917), Abalo E. Kulo (444125), Bonfoh Bassirou, Bonfoh, B, Lome, Swiss Tropical Inst, Bassirou Bonfoh (424496), Esther Schelling, Boukaya, G A, G Aboudou Boukaya, Bonfoh, Bassirou, Abalo E Kulo, Guillaume Fournié, Esther Schelling (113925), Boukaya, G. Aboudou, Fournié, Guillaume, Schelling, E, Fournié Guillaume, Schelling, Esther, Kulo, A E, Dean Anna S., Anna S Dean, Guillaume Fournié (160205), Dean, Anna S.   +32 more
core   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Institutions and Free Trade Agreements as Determinants of Trade Potential of India: a Stochastic Frontier Gravity Model Analysis [PDF]

Statistika: Statistics and Economy Journal
This study examines how institutions and free trade agreements affect India's actual export and import potential using a panel data set of 40 nations for the years 2000–2022.
Naseer Ul Hassan, Md. Sarafraz Equbal, Quaseen Jahan   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The impact of BRICS trade facilitation on China’s import and export trade in agricultural products

Frontiers in Sustainable Food Systems
Trade facilitation is essential for enhancing the import and export of agricultural products between China and BRICS countries. Improving trade efficiency and identifying potential opportunities contribute to establishing formal cooperation mechanisms ...
Gao Xin, Humayun Khan, Xin Ling
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A Study on Iran's Opportunities for Trade Integration with Central Asian Countries [PDF]

فصلنامه پژوهش‌های اقتصادی ایران, 2013
Due to increasing economic globalization and the need for greater global participation of countries, policy-makers and politicians throughout the world have broadly addressed the regional cooperation in the past two decades.
Behzad Doulati, Shukurov Buri Urakovich
doaj  

Evaluation of the export potential of Latvia with EU countries categorized by groups of goods

Forum Scientiae Oeconomia, 2018
The relevance of the research subject is related to the fact that exports are an integral part of the overall economic potential of any state and largely determine the pace of its economic development.
Erica Pancenko, Tatyana Ivanova
doaj   +1 more source