Results 51 to 60 of about 10,316,048 (305)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Hungary :New Potential Market

, 2019
I. Hungary : New Potential Market 1. Structural Changes in Hungarian Economy 2. Some Issues of Economic Policy 3. Foreign Trade 4. Trade between Hungary and South Korea II. Supplements 1. Structure of the Hungarian Banking System 2.

core   +1 more source

The Hidden Costs of Trade: Institutional and Cultural Determinants of Export Efficiency for Vietnam’s Wood Products

Economies
Vietnam’s wooden forest products industry is an important export sector, contributing to industrial growth and employment. However, it is facing increasing pressures related to challenges such as forest and export sustainability.
Phong Nguyen, Xuan Uyen Tran, Bonoua Faye   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Potential Directions for Expanding Russia’s Foreign Trade: An Econometric Analysis

Российский внешнеэкономический вестник
The paper examines the prospects for the development of Russia’s foreign trade with so-called “friendly” countries amid shifting economic conditions. Variations of the gravity model of international trade – both with and without a stochastic frontier ...
Furmanov Kirill K., Dubnovitskaya Anastasia A.   +1 more
doaj   +1 more source

Potential Conflicts between Agricultural Trade Rules and Climate Change Treaty Commitments [PDF]

, 2018
Climate change – among its many other challenges – also impacts on conditions of competition along the whole food value chain. This article posits that many mitigation and adaptation policies imply a differentiation between otherwise identical products ...
Häberli, Christian
core   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source