Results 31 to 40 of about 3,389,688 (248)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

How much trade cost will the ongoing US-China trade war generate for global value chains?

open access: yes, 2022
[Extract] The United States (US) and China represent the two largest economies in the World. Since China first entered the World Trade Organization (WTO) in 2001, its bilateral trade with US has grown exponentially, reaching 660 billion US dollars (USD ...
Wu, Jie, Wood, Jacob
core   +1 more source

The Impact of Trade War on Fiscal Revenue Through Trade Taxes in 5 Asian Countries

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
The trade war between the United States and China, which began in 2018, has triggered shifts in trade flows and the relocation of investments to various Asian countries.
Adin Salsabila   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Collateral Damage: Trade Disruption and the Economic Impact of War [PDF]

open access: yes
Conventional wisdom in economic history suggests that conflict between countries can be enormously disruptive of economic activity, especially international trade. Yet nothing is known empirically about these effects in large samples.
Alan M. Taylor, Reuven Glick
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Dampak Trade War Amerika Serikat VS China Terhadap Saham Syariah di Bursa Efek Indonesia

open access: yesEquilibrium: Jurnal Ekonomi Syariah, 2020
This study aims to determine the impact of the United States VS China trade war events on the performance of islamic stocks on shares incorporated in the index JII 2018 period by looking at the market reaction using 3 measurement proxies namely abnormal ...
Nor Hadi   +2 more
doaj   +1 more source

The conflicts of interests in the China-USA trade war

open access: yes, 2020
My thesis is to talk about the China-USA trade war. The trade war was started on March 22, 2018. I focus on the reason for the trade war and discuss whether the trade war is reasonable.
Hao, Pengfei
core  

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