Results 31 to 40 of about 16,744 (262)
Exhaustion of trademark rights and trademark law in EU [PDF]
Çalismanin baslangiç kisminda, fikri ve sinai mülkiyet haklarinin tarihçesi ve fikrisinai mülkiyet haklari kisaca anlatilmistir. Marka hakkinin tarihi süreç içerisindekigelisimi ile bu konuyla ilgili en önemli uluslararasi anlasmalar açiklanmistir.Çalismada ayrica markanin fonksiyonlari, marka hakkinin korumasi ve korunmakriterleri ile markanin ...
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
THE NOTORIOUS, REPUTED AND FAMOUS TRADEMARKS [PDF]
The owner of a trademark that has a reputation in Romania or in the European Union may request to court to forbid the infringer from using, without its consent, a sign identical or similar to its trademark, but for products or services different from ...
Andreea LIVĂDARIU
doaj
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Study on the Criteria for Judging Acquired Distinctiveness as a Result of Using the Trademark
This article contributes to the examination of recent developments, challenges, and controversies concerning the criteria for judging the distinctiveness of a mark acquired through use.
Taemin Eom
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Abstract This chapter deals with trademarks. Trademarks play a significant role in the FOSS ecosystem — while copyrights and patents are freely shared in FOSS licensing, trademarks are not. Free and open source software projects can, and therefore generally do, exercise their exclusive rights under trademark law.
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