Results 111 to 120 of about 59,422 (304)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

Intangible assets and competitiveness in Spain: an approach based on trademark registration data in Catalonia (1850-1946) [PDF]

open access: yes
This paper studies the origins of trademark registration in Spain and offers, for the first time, data across sectors and regions with a long-term perspective.
Fernández, Paloma, Sáiz, Patricio
core  

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

open access: yesAdvanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang   +15 more
wiley   +1 more source

THE INFLUENCE OF THE MADRID SYSTEM FOR THE INTERNATIONAL REGISTRATION OF MARKS ON THE DEVELOPMENT OF INTELLECTUAL PROPERTY

open access: yesМодернизация, инновация, развитие, 2015
This article shows the advantages of the Madrid System for the International Registration of Marks before registration trademark in the national office. Prospects for the use of this system for small and medium businesses.
I. A. Orlov
doaj  

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

This Name is Your Name: Public Landmarks, Private Trademarks, and Our National Parks [PDF]

open access: yes, 2017
To generations of Americans, Yosemite National Park and its landmarks have symbolized the core democratic ideals of the United States—spaces truly owned by the people and open to all.
Ault, Megan Elaine
core   +1 more source

Real‐Time In Vivo Visualization of Tumor‐Associated Macrophage Reprogramming Using a Nitric Oxide‐Activatable NIR‐II Nanoinducer

open access: yesAdvanced Science, EarlyView.
Reprogramming tumor‐associated macrophages is a promising therapeutic strategy for solid tumors. Here, a nitric oxide (NO)‐activatable NIR‐II fluorescence/photoacoustic nanoinducer (I/E@M2pep) that simultaneously facilitates and visualizes the repolarization of TAMs to an M1‐like phenotype is reported, thereby enhancing anti‐tumor efficacy through M1 ...
Qian Chen   +8 more
wiley   +1 more source

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

open access: yesAdvanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong   +13 more
wiley   +1 more source

THE MADRID PROTOCOL: MEWUJUDKAN PERLINDUNGAN HUKUM YANG EFEKTIF BAGI MEREK TERKENAL DI ASEAN

open access: yesJurnal Media Hukum, 2018
Intellectual Property Rights protection system is territorial. Registration and law enforcement must be done separately in each relevant jurisdiction. In the brand regime, this system is often a challenge for brand law enforcement.
rohaini rohaini
doaj  

Perlindungan Merek Dalam Pengembangan Usaha Kecil dan Menengah Bidang Ekonomi Kreatif di Indonesia

open access: yesZaaken
Indonesia is currently experiencing rapid development in the creative economy sector. Various industries such as design, fashion, art, music, film, and others have become the backbone of creative economic growth in this country. One of the most valuable
Faizah Bafadhal   +2 more
doaj   +1 more source

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