Results 111 to 120 of about 25,478 (302)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Understanding the legal landscape of non-conventional trademarks in India

open access: yesЦифровое право
Among contemporary intellectual property debates, non-conventional trademarks (such as sounds, smells, tastes, shapes, and holograms) present unique challenges.
S. Sheikh
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

WELL-KNOWN AND REPUTED TRADEMARK (OR FAMOUS TRADEMARKS) [PDF]

open access: yesChallenges of the Knowledge Society
According to the degree of awareness by the relevant public of the goods and/or services which they identify and whose commercial origin they guarantee, trademarks fall into two broad categories: (i) trademarks whose degree of awareness by the relevant
Viorel ROȘ, Andreea LIVĂDARIU
doaj  

PRODUCT DIFFERENTIATION PROTECTION: DEVELOPING A STRATEGY FOR MULTIPLE PRODUCERS OF REGIONAL SPECIALTY CROPS [PDF]

open access: yes
Specialty crops grown by multiple producers are often viewed by consumers as differentiated products that command a price premium. Since price premiums are dependent upon differentiation of an item from generic counterparts, specialty crops must have ...
Bryan, John T.   +2 more
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

The effective legal protection of the results of innovative activity as a factor of development

open access: yesСовременная наука и инновации
Innovations are now becoming more relevant and in demand. Every day, more and more companies around the world start a great innovation activity. But, like any other business, entrepreneurship requires protection.
M. V. Osipova, V. D. Frolova
doaj   +1 more source

From traditional trademark to atypical trademark : example of olfactory trademark

open access: yes, 2014
European law allows theoretically since 1988 the registration of all kind of trademarks, olfactory ones included. The legal protection of such signs using trademarks law became necessary with the birth of olfactory marketing. However, in the actual state of knowledge, the requirement by the European Court of Justice of a graphic representation as a ...
openaire   +1 more source

Trademarks

open access: yes, 1997
OpenGL is a trademark of Silicon Graphics, Inc. Autodesk CDK is a trademark of Autodesk, Inc. MS−DOS and Win32 are trademarks of Microsoft, Inc. Other product names are trademarks of the respective holders. Copyright © 1995−1997 by 3Dfx Interactive, Inc.

core  

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