Results 251 to 260 of about 167,734 (342)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Real-world Effectiveness of the Adjuvanted Recombinant Zoster Vaccine in ≥50-year-old Adults With Autoimmune Diseases. [PDF]

J Infect Dis
Constenla D, Lonnet G, Aris E, Rk R, Servotte N, Mwakingwe-Omari A, Alsdurf H, Yun H.   +7 more
europepmc   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Research priorities for stillbirth in Australia: outcomes of a national priority setting partnership. [PDF]

BMC Pregnancy Childbirth
Tindal K, Boyle F, Andrews C, Astell C, Yelland J, McIntyre S, Jenkinson B, Seeho S, Davies-Tuck M, Stuart-Butler D, Middleton P, Ellwood D, Gordon A, Flenady V.   +13 more
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Approximate quantum circuit compilation for proton-transfer kinetics on quantum processors.

Phys Chem Chem Phys
Kovyrshin A, Manawadu D, Altamura E, Pennington G, Jaderberg B, Brandhofer S, Nykänen A, Miller A, Talarico W, Knecht S, Pavošević F, Baiardi A, Tacchino F, Tavernelli I, Mensa S, Crain J, Tornberg L, Broo A.   +17 more
europepmc   +1 more source

Recent trends in the utilization of molecular breast imaging in the United States. [PDF]

Clin Imaging
Dave R, Gu L, Garrett HV, Bennett D, Stwalley D, Singer S, Chiu S, Lee MV.   +7 more
europepmc   +1 more source

Laws of the People’s Republic of China on Industrial and Intellectual Property [PDF]

, 1973
Haun, Kathryn A., Hsia, Tao-Tai
core   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the 'TreC Diabete' platform (TELEMECHRON Study). [PDF]

Front Clin Diabetes Healthc
Giovanazzi A, Gios L, Gentilini MA, Mastellaro M, Bartolotta P, Nicolussi Giacomaz L, Eccher C, Inchiostro S.   +7 more
europepmc   +1 more source