Results 31 to 40 of about 7,889 (262)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

RESEARCH ON THE EVOLUTION OF THE TOP ROMANIAN TRADEMARKS IN THE DOMESTIC MARKET [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2015
The paper analyzed the position of the Romanian trademarks using the data provided by Unlock Market Research Company in 2010 and 2014. The statistical parameters: average, variance, standard deviation and variation coefficient, and the Point Method and ...
Agatha POPESCU
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Exhaustion of trademark rights and trademark law in EU [PDF]

open access: yes, 2006
Çalismanin baslangiç kisminda, fikri ve sinai mülkiyet haklarinin tarihçesi ve fikrisinai mülkiyet haklari kisaca anlatilmistir. Marka hakkinin tarihi süreç içerisindekigelisimi ile bu konuyla ilgili en önemli uluslararasi anlasmalar açiklanmistir.Çalismada ayrica markanin fonksiyonlari, marka hakkinin korumasi ve korunmakriterleri ile markanin ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Study on the Scope and Limit of International Exhaustion

open access: yesJournal of Intellectual Property
Although Copyright Law includes provision for the exhaustion of distribution rights, other intellectual property laws do not explicitly address the exhaustion of rights.
SuCheol Kim
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis and Identification of Variables Affecting the Violation of Trademarks in the Field of E-Commerce in Iran [PDF]

open access: yesسیاست نامه علم و فناوری, 2020
Today, competition in business has led to more and more businesses using the field of electronics in business. Businesses operate in the web environment under their own brand. This trademark leads to the differentiation of the business from other similar
Mohamad Javad Jamshidi   +2 more
doaj  

Intellectual Property Rights in China—A Literature Review on the Public's Perspective

open access: yesFrontiers in Sociology, 2022
Despite significant advances in terms of the adoption of formal Intellectual Property Rights (IPR) protection, enforcement of and compliance with IPR regulations remains a contested issue in one of the world's major contemporary economies—China.
Katrin Muehlfeld, Mei Wang
doaj   +1 more source

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