Results 51 to 60 of about 167,734 (342)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

INFORMATION SYSTEM IN ORGANIZATIONS IMPLEMENTING THE NONCONVENTIONAL TECHNOLOGIES

open access: yesNonconventional Technologies Review, 2019
The ounce to a significant extent in the process of production in modern organizations of the energies produced by the use of nonconventional technologies represents a real advantage in obtaining a higher productivity and quality compared to the use of ...
Mihail Aurel Titu   +2 more
doaj  

NEW TYPES OF TRADEMARKS – PROTECTION OF MULTIMEDIA TRADEMARKS [PDF]

open access: yesChallenges of the Knowledge Society, 2019
The Directive (EU) 2015/2436 of the European Parliament and of the Council of 16 December 2015 to approximate the laws of the Member States relating to trademarks.and the Regulation (EU) 2017/1001 of the European Parliament and of the Council of 14 June
George-Mihai IRIMESCU
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

To blend so as to brand: a study of trademarks and brand names

open access: yesLexis: Journal in English Lexicology, 2019
Brand names represent valuable linguistic assets. They serve a variety of purposes, from product differentiation to corporate identity. Creativity and wit are employed in brand naming practices, frequently resulting in the formation of blends.
Jelena Danilović Jeremić   +1 more
doaj   +1 more source

The True Colors of Trademark Law: Green-lighting a Red Tide of Anti Competition Blues [PDF]

open access: yes, 2008
The elevation of color to stand-alone trademark status illustrates the unbounded nature of trademarks within the judicial consciousness. The availability of color-alone marks also facilitates the commoditization of color in ways that complicate the ...
Bartow, Ann
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Implementation of Well-Known Trademarks Doctrine in Indonesian Commercial and Supreme Court

open access: yesFiat Justisia, 2021
The implementation of well-known trademark in indonesia is still unsatisfying especially for foreign trademarks since many foreign trademarks that claimed themselves as well-known trademarks were not admitted for the trademarks were not yet registered or
Sujana Donandi S., Pandu Adi Cakranegara
doaj   +1 more source

Avoiding Intellectual Property Problems [PDF]

open access: yes, 2001
Patents, copyrights, trademarks, as well as trade secrets and related rights can be used to exclude free riders. These rights are usually collectively called intellectual property or IP.
Field, Thomas G., Jr.
core   +1 more source

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