Results 61 to 70 of about 7,890 (262)

Assessing the Legal Feasibility of Trademark Protection in the Metaverse Through Registration [PDF]

open access: yesپژوهشنامه حقوق تطبیقی
The metaverse, a virtual world parallel to the physical environment, presents new opportunities for business owners. However, the emergence of this new realm also poses challenges for intellectual property rights holders, particularly trademark owners ...
Saeed Habiba, Mohammad Milad Khani
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Domain Name: Digital Asset, Identifier, or Some Other Kind of Object?

open access: yesЦифровое право
This article is dedicated to a comprehensive analysis of the legal nature of a domain name as a special object functioning in the digital environment and proactively involved in civil commerce.
I. E. Titov, E. V. Alymova
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Perceived Benefits of Trademark Infringement Law to Thai Sports Industry [PDF]

open access: yesAnnals of Applied Sport Science, 2020
Background. The sports industry is comprised of a multitude of for-profit and non-profit organizations. It is therefore unsurprising that there are disputes between organizations and that some of these disputes center on the use of trademarks ...
Oam To-aj, Prasertchai Suksa-ard
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Is ADR suitable for the resolution of intellectual property disputes?

open access: yesInternational Review of Law, 2017
Intellectual property (IP) is the branch of law that protects innovations and creations, such as new technological inventions, literary, artistic and musical creations, distinctive signs, computer programs, trade secrets, microchips and geographical ...
محمد سالم أبو الفرج
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

The effective legal protection of the results of innovative activity as a factor of development

open access: yesСовременная наука и инновации
Innovations are now becoming more relevant and in demand. Every day, more and more companies around the world start a great innovation activity. But, like any other business, entrepreneurship requires protection.
M. V. Osipova, V. D. Frolova
doaj   +1 more source

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