Results 81 to 90 of about 7,890 (262)
WELL-KNOWN AND REPUTED TRADEMARK (OR FAMOUS TRADEMARKS) [PDF]
According to the degree of awareness by the relevant public of the goods and/or services which they identify and whose commercial origin they guarantee, trademarks fall into two broad categories: (i) trademarks whose degree of awareness by the relevant
Viorel ROȘ, Andreea LIVĂDARIU
doaj
THE AGREEMENT ON TRADE-RELATED ASPECTS OF INTELLECTUAL PROPERTY RIGHTS (TRIPS)
The paper delves into the development and intricacies of international legal frameworks for intellectual property (IP) rights protection and commercialization, focusing on agreements like the Paris and Berne Conventions.
Alina BABA
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Este artículo trata de los problemas de marcas y competencia desleal que genera el uso de metatags en las páginas Web en la jurisprudencia norteamericana y su posible aplicación en el sistema jurídico españolThis article discusses the problems that the ...
Carlos Amunátegui Perelló
doaj
A Study on the Sublicensing System of Intellectual Property Rights
Sublicensing in the context of intellectual property rights refers to a license granted by a licensee to a third party under the authority granted to the licensee.
Sucheol Kim
doaj +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
From traditional trademark to atypical trademark : example of olfactory trademark
European law allows theoretically since 1988 the registration of all kind of trademarks, olfactory ones included. The legal protection of such signs using trademarks law became necessary with the birth of olfactory marketing. However, in the actual state of knowledge, the requirement by the European Court of Justice of a graphic representation as a ...
openaire +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source

