Results 41 to 50 of about 5,710,671 (298)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Studying indicators of traditional architecture of Shiraz houses in order to provide a suitable model for contemporary housing design in order to use clean energy [PDF]

تحقیقات کاربردی علوم جغرافیایی, 2023
rchitecture is always influenced by various indicators, the most important of which are climatic and physical-spatial indicators. These indicators are well observed in traditional homes and have played an important role in the use of clean energy.
tara heidari orojloo, afshin ghorbani param, faramarz hasanpour   +2 more
doaj  

Traditional architecture

, 2020
Traditional architecture displaces all possible thoughts about the need for more complicated houses and buildings. Strongly taking the position of natural architecture - it has become the foundation of all sorts of styles and cultures in architecture. The article talks about the origin and development of traditional architecture.
El Alaoui S., Abbad F., Khalabi S., Zhukova T.   +3 more
openaire   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

KOSMOLOGI DALAM ARSITEKTUR TORAJA

Dimensi: Journal of Architecture and Built Environment, 2001
Modernism in architecture always has a concrete, profane and clear concept.On the totally contrary, traditional architecture traditional has an abstract, spiritual and often religious concept or way of thinking.
Yulianto Sumalyo
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Innovative Approaches to the Restoration and Revitalization of Historical Bazaars: Preserving Heritage, Enabling Sustainability [PDF]

Journal of Design Thinking
The Kerman Bazaar and its historical fabric, with a long-standing history, harbor a unique treasure of various architectural styles. This historical fabric, similar to its counterparts in other cities, faces numerous social, economic, and structural ...
Safoura Rouhi, Mahdi Sadoddin
doaj   +1 more source

A prelude to new ways of thinking about traditionalism

Journal of Traditional Building, Architecture and Urbanism, 2020
Lucien Steil’s book In the Mood for Architecture, Tradition, Modernism & Serendipity offers an illuminating and refreshing perspective on contemporary traditional architecture, and what it stands for today.
Victoria Schulz-Daubas
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source