Results 51 to 60 of about 1,274,066 (289)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Performance Characterization of In-Memory Data Analytics on a Modern Cloud Server

, 2015
In last decade, data analytics have rapidly progressed from traditional disk-based processing to modern in-memory processing. However, little effort has been devoted at enhancing performance at micro-architecture level.
Awan, Ahsan Javed, Ayguade, Eduard, Brorsson, Mats, Vlassov, Vladimir   +3 more
core   +1 more source

Traditional architecture

, 2020
Traditional architecture displaces all possible thoughts about the need for more complicated houses and buildings. Strongly taking the position of natural architecture - it has become the foundation of all sorts of styles and cultures in architecture. The article talks about the origin and development of traditional architecture.
El Alaoui S., Abbad F., Khalabi S., Zhukova T.   +3 more
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Design strategies for the street spaces of fishing village based on traditional architectural typology: the case of Limin Village in Ningbo of coastal China

Journal of Asian Architecture and Building Engineering
Village street spaces are the core area of villagers’ life and production, which have the important functions of cultural inheritance and historical memories.
Xuan Zhou, Caixia Gao
doaj   +1 more source

Borobudur was Built Algorithmically [PDF]

, 2010
The self-similarity of Indonesian Borobudur Temple is observed through the dimensionality of stupa that is hypothetically closely related to whole architectural body.
Situngkir, Hokky
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

BigDataBench: a Big Data Benchmark Suite from Internet Services

, 2014
As architecture, systems, and data management communities pay greater attention to innovative big data systems and architectures, the pressure of benchmarking and evaluating these systems rises.
Gao, Wanling, He, Yongqiang, Jia, Zhen, Li, Xiaona, Lu, Gang, Luo, Chunjie, Qiu, Bizhu, Shi, Yingjie, Wang, Lei, Yang, Qiang, Zhan, Jianfeng, Zhan, Kent, Zhang, Shujie, Zheng, Chen, Zhu, Yuqing   +14 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

An Ethnographic Interpretation of the Hidden Thermal Pleasure in the Architectural Tradition of Desert Climate [PDF]

مسکن و محیط روستا, 2021
The architectural tradition of desert climate has both visible and hidden lessons within itself. The creation of rich sensory spaces is one of the gifts that the architecture of this climate offers.
Fatemeh Akrami, Mohammad Hossein Ayat allahi, Hossein Afrasiyabi   +2 more
doaj