Results 131 to 140 of about 3,154,939 (307)

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions

Cell Death and Disease
The aberrant upregulation of Yes-associated protein 1 (YAP1) in a variety of solid cancers contributes to tumor progression and poor clinical outcomes, rendering it an appealing therapeutic target.
Lei Huang, Yalei Wen, Qin Guo, Caishi Zhang, Xiao Yang, Mei Li, YiXia Liu, Xinying Li, Jiaxin Tang, Xiaofeng Zhou, Qi Qi, Haoxing Zhang, Tongzheng Liu   +12 more
doaj   +1 more source

Development and initial validation of the career resilience instrument for CDC emergency responders in China within the context of public health emergencies: based on a survey conducted in Shanghai

Frontiers in Public Health
BackgroundChina faces various public health emergencies, and emergency responders at the Centers for Disease Control and Prevention (CDC emergency responders) are a mainstay in responding to public health emergencies.
An-Qi Wang, Wen-Di Cheng, Yu-Yan Fu, Ya-Shuang Luo, Juan Li, Hai-Yin Wang, Chun-Lin Jin   +6 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

WeChat usage and preservation of cognitive functions in middle-aged and older Chinese adults: indications from a nationally representative survey, 2018–2020

BMC Public Health
Purpose To investigate the associations between the most popular social media platform WeChat usage and cognitive performance among the middle-aged and older Chinese population using data from a nationally representative survey.
Yan Zhou, KaiweiSa Abuduxukuer, Chuchu Wang, Jin Wei, Wenming Shi, Yongzhen Li, Guang Huang, Yifan Zhou, Yunfeng Zhang, Jianfeng Luo   +9 more
doaj   +1 more source

Hepatic microcirculatory disturbance in liver diseases: intervention with traditional Chinese medicine

Frontiers in Pharmacology
The liver, a complex parenchymal organ, possesses a distinctive microcirculatory system crucial for its physiological functions. An intricate interplay exists between hepatic microcirculatory disturbance and the manifestation of pathological features in ...
Pei Liu, Pei Liu, Wan-Li Liang, Wan-Li Liang, Rui-Ting Huang, Rui-Ting Huang, Xin-Xing Chen, De-Hua Zou, De-Hua Zou, Hiroshi Kurihara, Yi-Fang Li, You-Hua Xu, Shu-Hua Ouyang, Rong-Rong He, Rong-Rong He   +14 more
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Targeting CDK4/6 suppresses colorectal cancer by destabilizing YAP1

MedComm
Colorectal cancer (CRC) is among the most prevalent and deadly cancers worldwide. The Yes‐associated protein 1 (YAP1) is frequently dysregulated in cancers, contributing to cancer stemness, chemoresistance, and cancer‐related death.
Yalei Wen, Xiao Yang, Shengrong Li, Lei Huang, Jiayi Chen, Lirong Tan, Xiuqing Ma, Yingjie Zhu, Zhengqiu Li, Changliang Shan, Chunze Zhang, Qiushi Zhang, Mingchao Liang, Haoxing Zhang, Tongzheng Liu   +14 more
doaj   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Impact Assessment of Technologies That Mitigate Adverse Circumstances: The Case of Disease-Resistant Beans in Honduras [PDF]

Constructing appropriate counterfactual scenarios is an ongoing challenge for impact assessment of agricultural research. Using farm-level survey data from Honduras, this paper adapts the Heckman two-step procedure to construct the counterfactual to ...
Mather, David, Oehmke, James F.
core   +1 more source