Results 31 to 40 of about 683,044 (286)

Research advances of Chinese medicine in preventing and treating diabetic nephropathy and renal fibrosis

Linchuang shenzangbing zazhi, 2021
Renal fibrosis is a major pathological change in the development and progression of various diseases such as diabetic nephropathy（DN）,glomerulonephritis, hypertensive nephropathyand end-stage renal disease.It is also one of the important causes of renal ...
Cao Liu-yang, Yu Hai-yuan
doaj  

Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine. [PDF]

, 2019
Rising concerns about the short- and long-term detrimental consequences of administration of conventional pharmacopeia are fueling the search for alternative, complementary, personalized, and comprehensive approaches to human healthcare.
Dethlefs, Brent A, Lee, Katherine L, Li, Shengwen Calvin, Loudon, William G, Luo, Jane, Su, Qingning, Zhang, Junjie   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Chinese Guidelines for the Management of Acne Vulgaris: 2019 Update#

International Journal of Dermatology and Venerology, 2019
. The first Chinese guidelines for the management of acne vulgaris was developed and published in 2008 and updated in 2015. With the acquisition of new evidence-based data and the development of new medicines and techniques, the guidelines should be ...
Acne Group, Combination of Traditional and Western Medicine Dermatology; Acne Group, Chinese Society of Dermatology; Acne Group, Chinese Dermatologist Association; Acne group, Dermatology Committee, Chinese Non-government Medical Institutions Association
doaj   +1 more source

Traditional Chinese medicine compound Erxian soup extract with menopausal cognitive function [PDF]

, 2012
The invention relates to modern pharmacology research in traditional Chinese medicines, in particular to a traditional Chinese medicine compound Erxian soup extract with a menopausal cognitive function.

core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Observation of antitumor mechanism of GE11-modified paclitaxel and curcumin liposomes based on cellular morphology changes

AAPS Open
Curcumin and paclitaxel are widely used as anti-tumor hydrophobic model drugs for the designation of smart tumor-targeting nanocarriers and the study of the correlation between structural characteristics of nanoparticles and in vivo therapeutic efficacy.
Hailing Tang, Lijuan Li, Baoshan Wang, Guangxi Scientific Research Center of Traditional Chinese Medicine   +3 more
doaj   +1 more source

Reflections on Traditional Chinese Medicine's Modernization

Yixue yu zhexue
The concept of cultural tradition emphasizes the intrinsic cultural genes of tradition, while traditional culture focuses more on the socio-cultural conditions of the present, highlighting the temporal and contextual presence of culture.
Weihua PENG
doaj   +1 more source

Potential effectiveness of traditional Chinese medicine for cardiac syndrome X (CSX): a systematic review and meta-analysis [PDF]

, 2013
BACKGROUND: Treatment of cardiac syndrome X with unknown pathological mechanism remains a big challenge for clinicians. Complementary and alternative medicine may bring a new choice for its management.
Hongcai Shang, Jia-ying Wang, Jing Chen, Jing-bo Zhai, Jing-yuan Mao, Lu Xiao, Wei Mu   +6 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source