Results 181 to 190 of about 54,879 (249)

Metabolic Mechanisms of Modified Lingguizhugan Decoction in Obesity and Lipid Metabolism Disorders: A Multi‐Omics Approach

open access: yesObesity Science &Practice, Volume 12, Issue 4, August 2026.
In this study, we explore the effects of Modified Lingguizhugan Decoction (MLGZGD) on obesity and lipid metabolism in mice, using a multi‐omics approach. Our results show that MLGZGD modulates gut microbiota composition, including beneficial genera like Akkermansia, and improves lipid metabolism by regulating triglyceride and phosphatidylcholine levels.
Fufu Li   +9 more
wiley   +1 more source

Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak   +4 more
wiley   +1 more source

Multi‐Omics Analysis Identifies Tryptophan Metabolism and Glycolysis as Potential Pathways Involved in the Protective Effects of Tormentic Acid Against Metabolic Associated Fatty Liver Disease

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
TA alleviates MCD diet‐induced MAFLD, and this effect is associated with alterations in tryptophan metabolism and glycolysis. ABSTRACT Metabolic associated fatty liver disease (MAFLD) has high morbidity and tragically lacks effective therapeutic remedies.
Yuanyuan Wei   +6 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Structure–Property Relationships of Atmospheric Water Harvesting for Water‐Carbon‐Energy Sustainability

open access: yesSmall Structures, Volume 7, Issue 8, August 2026.
This review discusses the integration of advanced characterization, computational modeling, and multifunctional atmospheric water harvesting (AWH) systems for sustainable water‐energy‐carbon solutions. These methods reveal structure‐property relationships, guiding next‐generation hygroscopic material design.
Miao Tang, Huan Liu, Mitch Guijun Li
wiley   +1 more source

The Journey of Studying Kampo Medicine in Japan Through the Eyes of an Israeli Acupuncturist and Kampo Practitioner

open access: yesTraditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Objective To highlight the stark contrasts in the integration, regulation, and practice of traditional medicine between the two countries (Israel and Japan). Methods This article chronicles the personal and professional journey of an Israeli acupuncturist studying Kampo medicine in Japan. Through personal experience as a visiting researcher at
Yonatan Klein   +11 more
wiley   +1 more source

Encounters With Traditional Medicine and Further Multidisciplinary and International Cooperation

open access: yesTraditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Background The integration of traditional medicine (TM) into modern healthcare has gained global momentum. Following the inclusion of TM in the 11th revision of the International Classification of Diseases, multidisciplinary and international cooperation has become increasingly essential.
Kokoro Ichihara   +6 more
wiley   +1 more source

Jiuwei Xiaozhi Decoction Alleviates High‐Fat Diet‐Induced MASLD by Suppressing Hepatic SREBP2‐Driven Cholesterogenesis and Restoring PPARα‐Mediated Fatty Acid Oxidation

open access: yesChemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Studies have found that Jiuwei Xiaozhi Decoction can improve high‐fat diet‐induced fatty liver disease, mainly by regulating the SREBP2 and PPARα pathways to balance hepatic lipid metabolism while reducing inflammatory responses. ABSTRACT Jiuwei Xiaozhi Decoction (JWXZ) is a nine‐herb traditional Chinese medicine formula clinically used for hepatic ...
Youcheng Ma   +5 more
wiley   +1 more source

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