Results 191 to 200 of about 54,235 (259)
The present studies of network pharmacology, molecular docking and molecular dynamics simulation indicated that liensinine might ameliorate oxidative damage to vascular endothelium (ODVE) by regulating the targets of Nrf2, which is encoded by the NFE2L2 gene. Then the in vitro study further showed that liensinine exhibited an obvious protection against
Feng Gao +7 more
wiley +1 more source
This study systematically characterizes extracellular vesicle‐like particles (EVLPs) from three processed Gastrodia elata forms (dry, wine, and ginger), evaluating their physicochemical properties, metabolite profiles, biocompatibility, and neuroprotective efficacy in an OGD/R model, highlighting their neuroprotective potential as a functional food ...
Yuanyuan Qin +10 more
wiley +1 more source
The completion and output of NSFC‐funded medical projects reflect national strategic orientations and disciplinary development laws. It is suggested to establish a dynamic evaluation mechanism, promote the “basic research‐application‐transformation” collaborative model, support small‐scale yet high‐efficiency fields, and conduct long‐term tracking of ...
Hu Jin, Huang Hui, Bao Xinjie, Bai Hua
wiley +1 more source
Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad +4 more
wiley +1 more source
ABSTRACT Background and Aims There is evidence of the beneficial effects of acupuncture in the treatment of polycystic ovary syndrome (PCOS). This study aimed to compare acupuncture with clomiphene in ovulation induction among infertile women with PCOS.
Leili Hafizi +7 more
wiley +1 more source
ABSTRACT Background and Aims High‐quality sleep, calmness, and lack of fatigue are vital for the health of critical hospital staff. Operating room personnel experience significant mental and physical stress, including anxiety and sleep disturbances.
Rana Abjar +4 more
wiley +1 more source
TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley +1 more source
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang +13 more
wiley +1 more source
Progress of metabolomics‐centric multi‐omics research in medicine
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang +6 more
wiley +1 more source

