Results 191 to 200 of about 54,879 (249)
Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.The graphical abstract illustrates the action mechanisms through which PPE alleviates HUA by inhibiting XOD activity, and by suppressing the PI3K‐AKT signaling pathway to downregulate the expression of the urate reabsorption transporters URAT1 and GLUT9, thereby promoting renal UA excretion and attenuating renal injury.
Zeyu Yin +6 more
wiley +1 more source
Exploring legal‐ and health‐risk messaging to reduce demand for elephant skin
Conservation Biology, Volume 40, Issue 4, August 2026.Abstract Asian elephants (Elephas maximus) are poached for an illegal trade in their skins, which are used in traditional medicine in Africa and Asia. We explored whether messages about the legal and health risks of using elephant skin for medicinal purposes (stomach illness) could reduce such consumption.
Beilu Duan +10 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 8, August 2026.Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song +15 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 8, August 2026.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Mechanisms and Research Progress of Leech in Diabetic Ulcer Fibrosis
International Wound Journal, Volume 23, Issue 8, August 2026.ABSTRACT Delayed wound healing is a major complication of diabetes, with its core pathological process being pathological fibrosis driven by persistent inflammation, metabolic disorders and vascular dysfunction under hyperglycemia. This process involves pathological retention of inflammatory cells, abnormal expression of pro‐fibrotic factors, and ...
Yanchun Wang +3 more
wiley +1 more source
Journal of Clinical Nursing, Volume 35, Issue 8, Page 3335-3356, August 2026.ABSTRACT Background Cough, a prevalent and debilitating symptom of lung cancer, remains poorly managed. Accumulating evidence on non‐pharmacological interventions for lung cancer cough necessitates systematic evaluation to assess their efficacy. Aim To synthesise evidence on non‐pharmacological interventions for managing cough in lung cancer patients ...
Mengyao Cao +4 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 14, 31 July 2026.Hyperglycemia upregulates CTRP1 and SGLT2 in renal tubular cells, promoting glucose influx, CTRP1‐mediated glucotoxic stress, and tubular senescence in diabetic kidney disease. In the experimental model, SGLT2 inhibition with dapagliflozin was associated with reduced glucose uptake, attenuation of tubular senescence, suppression of CTRP1‐related ...
Lina Gu +6 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7622-7625, August 2026.
Alessandro Milia +5 more
wiley +1 more source