Results 211 to 220 of about 75,375 (316)

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

Computational screening and molecular docking of compounds from Traditional Chinese Medicine (TCM) by targeting DNA topoisomerase I to design potential anticancer drugs. [PDF]

PLoS One
Shimu MSS.
europepmc   +1 more source

Asiatic Acid Ameliorates MNNG‐Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis

Phytotherapy Research, Volume 40, Issue 5, Page 2210-2229, May 2026.
ABSTRACT Chronic atrophic gastritis (CAG), a widespread gastrointestinal condition, is widely acknowledged as a precursor to gastric cancer (GC). The incidence of CAG has been steadily increasing, yet effective pharmacological interventions remain unavailable.
Feifei Zhou, Cuiyu Zhu, Wanwan Yuan, Wenkun Peng, Qianqian Xu, Hongli Yang, Ruofan Cao, Ben Wang, Meiqian Wang, Hongwei Xu   +9 more
wiley   +1 more source

Medcheck: a novel software for automated de-formulation of traditional Chinese medicine (TCM) prescriptions by liquid chromatography-mass spectrometry. [PDF]

J Pharm Anal
Li XL, Zhang JQ, Li Y, Shen XJ, Yang HY, Yang L, Xu M, Bi QR, Yao CL, Guo DA.   +9 more
europepmc   +1 more source

DNA Methylation Regulates CDK5R1 and NRBP1 to Exert Effects on Alcohol Dependence: Insights From Mendelian Randomization

Addiction Biology, Volume 31, Issue 5, May 2026.
This study employed integrative Mendelian Randomization analysis to identify 10 drug‐targetable genes with altered expression in alcohol dependence. Colocalization evidence suggests shared causal variants. Crucially, DNA methylation at specific sites (cg07437263, cg05102552) mediates risk by upregulating the protective gene CDK5R1 (63.92%) and ...
Fuyuan Deng, Junsheng Peng, Siran Lai, Guangpeng Zhang, Miaomiao Li, Yuxin Huang, Mi Yuan, Gaolei Yao, Peiming Zhang, Liming Lu   +9 more
wiley   +1 more source

Traditional Chinese Medicine Ameliorates Depression via the Gut-Brain Axis: A Review Focus on NLRP3/TLR4-Mediated Inflammatory Pathways and Gut Microbiota Modulation

Neuropsychiatric Disease and Treatment
Longfei Che,1 Jiaming Xie,2 Chunlei Xia,1 Qinming Yu3 1Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, 150040, People’s Republic of China; 2Yangsheng College of Traditional Chinese Medicine, Guizhou University of ...
Che L, Xie J, Xia C, Yu Q
doaj  

International Evidence‐Based Guidelines for Traditional Chinese Medicine Management of Allergic Rhinitis

Allergy, Volume 81, Issue 5, Page 1334-1353, May 2026.
ABSTRACT Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies.
Qin‐Wei Fu, Peng Liu, Yan Ruan, Xin‐Rong Li, Lan‐Zhi Zhang, Sha‐Sha Yang, Feng Chai, Ji Chen, Qiao‐Yan Chen, Shu‐Cheng Chen, Wen‐Yong Chen, Yong‐Na Chen, Hong‐Bin Cheng, Lei Cheng, Lu‐Jia Cui, Ke‐Bin Deng, Cai‐Shan Fang, Rong‐Chang Feng, Li Fu, Wen‐Yang Fu, Jian‐Ying Gao, Hong Guo, Miao He, Ko‐Hsin Hu, Chun‐Jiang Huang, He‐Yin Huang, Lu‐Yun Jiang, Feng‐Ying Qiao, Hui Leng, Yun‐Ying Li, Chun‐Song Liu, Da‐Xin Liu, Jian‐Hua Liu, Jin‐Hui Liu, Jing Liu, Min Liu, Wei‐Ting Liu, Yuan‐Xian Liu, Yang Liu, Ying Liu, Zhi‐Qing Liu, Qiu‐Lan Luo, Yu Ma, De‐Hong Mao, Juan Meng, Kai‐Yun Pang, Shun‐Lin Peng, Xuan‐Fu Tong, Ji Wang, Jia‐Xi Wang, Jun‐Ge Wang, Ren‐Zhong Wang, Shi‐Zhen Wang, Ji‐Yan Xia, Hui Xie, Qiang Xie, Yan Xie, Da‐Jing Xiong, Zhan‐Feng Yan, Hui Yang, Da‐Zheng Zhang, Fu‐Bing Zhang, Shi‐Peng Zhang, Zhi‐Cheng Zhang, Ji‐Ping Zhao, Yu Zhao, Yun Zheng, Dan‐Zhu Zhong, Li Zhou, Valentin Mikhailovich Knyazev, Irina Viktorovna Kostrova, Wing‐Fai Yeung, Qi Wang, De‐Yun Wang, Qin‐Xiu Zhang   +74 more
wiley   +1 more source

Repurposing Hetrombopag for Multiple Myeloma by Targeting PNPO: A Celastrol‐Inspired Approach

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.
Hetrombopag targeted PNPO to inhibit multiple myeloma. ABSTRACT Multiple myeloma (MM) is a malignancy of plasma cells whose excessive immunoglobulin production elevates reactive oxygen species (ROS), promoting pathogenesis. Active compounds from Traditional Chinese Medicine, such as celastrol, can exert antitumour effects by further increasing ROS ...
Tianyi Yu, Cheng Wang, Jingru Xie, Yongxin Wei, Hongwei Cui, Huaxia Zhang, Fan Zhou, Zhendong Deng, Ye Yang, Chunyan Gu   +9 more
wiley   +1 more source

The correlation between the traditional Chinese medicine (TCM) syndrome and the concentration of adiponectin and peroxynitrite in dyslipidemia patients

, 2016
Jing Chen, Chao Ye, Zheng Yang, Xiaolin Xue, Qingling Sun, Pinhui Li, Huimin Yang   +6 more
openalex   +1 more source