Results 231 to 240 of about 7,584,615 (297)
Analytical Science Advances, Volume 7, Issue 2, December 2026.ABSTRACT This study compared the pharmacokinetics of six constituents from Danggui Jixueteng Decoction in normal versus carboplatin‐induced myelosuppressive rats. A rapid, sensitive ultra‐high performance liquid chromatography‐tandem mass spectrometry method was developed and validated for simultaneous quantification of six diverse constituents (8‐O ...
Mingxin Guo +3 more
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Biomedical Chromatography, Volume 40, Issue 12, December 2026.ABSTRACT An ultrahigh‐performance liquid chromatography coupled with quadrupole‐Orbitrap high‐resolution mass spectrometry (UHPLC‐Q‐Orbitrap HRMS) method was applied to characterize Pingchuanning (PCN) decoction and its absorbed serum constituents in asthmatic rats.
Yue Zhang +6 more
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Counselling and Psychotherapy Research, Volume 26, Issue 4, December 2026.ABSTRACT Background Hindering self‐focused attention (HSA) refers to momentary experiences of internal self‐focus involving cognitive, emotional and bodily disruptions that may heighten vulnerability to stress among counsellors‐in‐training. Previous research has primarily been cross‐sectional and conducted in Western training contexts, limiting ...
Catherine M.‐H. Toh +2 more
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Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
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Brain and Behavior, Volume 16, Issue 11, November 2026.ABSTRACT Objective Employing network pharmacology prediction combined with experimental validation, this research elucidated the underlying mechanisms of Shexiang Huayu Xingnao granules (SXHY) against intracerebral hemorrhage (ICH). Methods Potential targets and related signaling pathways of SXHY acting on ICH were predicted through network ...
Yuan RuKui +4 more
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Food Science &Nutrition, Volume 14, Issue 11, November 2026.Tiaoqi Daozhi Decoction (TQDZD) is a classic formulation composed of eight medicine‐food homologous botanicals. UPLC‐MS/MS profiling identified 1962 non‐redundant compounds in its aqueous extract, predominantly phenolic acids and flavonoids, of which 107 metabolites were systemically bioavailable.
Min Duan +4 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.Tumor‐derived exosomal factors prime cardiomyocytes for ferroptosis by suppressing the GPX4–SLC7A11–Nrf2 antioxidant axis, depleting glutathione, and promoting iron‐dependent lipid peroxidation. While PD‐1 blockade alone induces only mild oxidative stress, it acts synergistically with tumor signals to markedly amplify ferroptosis, leading to ...
Xiaohua Ma +5 more
wiley +1 more source
Stemonine Alleviates UVB‐Induced Keratinocyte Senescence by Activating SIRT3
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.Stemonine, a natural alkaloid, protects human HaCaT keratinocytes against UVB‐induced skin senescence. Stemonine attenuated oxidative stress, mitochondrial dysfunction, DNA damage, and key senescence markers. It functioned by upregulating the expression and activity of SIRT3.
Kun Chen +6 more
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Pan‐Cancer Landscape of TMEM9 With Experimental Validation in Head and Neck Squamous Cell Carcinoma
The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.Transmembrane protein 9 (TMEM9) was investigated across cancers using public transcriptomic, clinical, genomic, and immune datasets, followed by functional validation in head and neck squamous cell carcinoma (HNSC). TMEM9 showed cancer‐dependent expression, diagnostic discrimination, prognostic associations, and relationships with immune infiltration ...
Mi Wang +3 more
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Starch - Stärke, Volume 78, Issue 11, November 2026.This study provides evidence that Polygonatum cirrhifolium polysaccharides possesses significant immunomodulatory, antifatigue, and hypoxia‐tolerance effects. The findings suggest that the MAPK/NF‐κB signaling pathway may be involved in its immunoregulatory actions and that PCP could be a promising candidate for enhancing physical performance and ...
Jun Nan +4 more
wiley +1 more source