Results 21 to 30 of about 54,879 (249)

Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl4/2-AAF

Pharmaceutical Biology, 2021
Context Our previous studies indicated that Yiguanjian decoction (YGJ) has an anti-hepatic-fibrosis effect and could regulate macrophage status. Objective To elucidate the mechanism of YGJ in regulating macrophages.
Ying Xu, Wen Xu, Wei Liu, Gaofeng Chen, Shili Jiang, Jiamei Chen, Xun Jian, Hua Zhang, Ping Liu, Yongping Mu   +9 more
doaj   +1 more source

Expert Consensus on Clinical Research Methodology of Traditional Chinese Medicine in the New Era

Xiehe Yixue Zazhi, 2022
To address the challenges of the new era and promote the rational application of clinical epidemiology and evidence-based medicine methods in traditional Chinese medicine (TCM), Chinese Medicine Group, the Clinical Epidemiology and Evidence-based ...
Chinese Medicine Group, Clinical Epidemiology and Evidence-based Medicine Association of Chinese Medical Association
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Development and validation of a nomogram model integrating noninvasive detection of radial pulse wave for predicting diabetic foot risk in type 2 diabetes mellitus

Frontiers in Endocrinology
BackgroundThis study aimed to develop and evaluate a nomogram model based on Traditional Chinese Medicine (TCM) pulse mapping parameters to predict the risk of diabetic foot (DF) in patients with type 2 diabetes mellitus (T2DM).MethodsA retrospective ...
Yuting Huo, Wen Li, Ai Xu, Siman Wang, Yuqing Wang, Jin Xu, Rui Guo, Cheng Zhao, Haixia Yan   +8 more
doaj   +1 more source

Network Meta-analysis of efficacy of integrated traditional Chinese and western medicine for acute kidney injury

Linchuang shenzangbing zazhi, 2022
ObjectiveTo compare the therapeutic efficacy of western medicine versus different traditional Chinese medicines （TCM） for acute kidney injury （AKI） patients.MethodsLiterature items were retrieved from the databases of CNKI， Wanfang and Sinomed.
Luo Pu-chang, Chen Hong-bo
doaj  

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Effect and Molecular Mechanisms of Traditional Chinese Medicine on Tumor Targeting Tumor-Associated Macrophages

Drug Design, Development and Therapy, 2020
Jing He, 1 Peihao Yin, 1–4 Ke Xu 1, 3, 4 1Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Department of General Surgery, Putuo Hospital, Shanghai University of Traditional Chinese ...
He J, Yin P, Xu K
doaj  

TCM-Grid: Weaving a Medical Grid for Traditional Chinese Medicine [PDF]

, 2003
We present a TCM-Grid for Traditional Chinese Medicine (TCM). The purpose of the TCM-Grid is to aid the development of distributed systems that help health professionals, researchers, enterprizes and personal users to retrieve, integrate and share TCM information and knowledge from geographically decentralized TCM database resources and knowledge base ...
Huajun Chen, Zhaohui Wu 0001, Chang Huang, Jiefeng Xu   +3 more
openaire   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Methodological Aspects of Traditional Chinese Medicine (TCM)

Annals of the Academy of Medicine, Singapore, 2006
The efficacy of Traditional Chinese Medicine (TCM) is less well-established than many believe and needs to be more firmly established through clinical trials. Such studies should adhere to the currently accepted standards. When planning and conducting clinical trials, one encounters numerous logistical and methodological problems.
openaire   +2 more sources