Results 31 to 40 of about 54,235 (259)

AI drug discovery tools and analysis technology: New methods aid in studying the compatibility of Traditional Chinese Medicine

Pharmacological Research - Modern Chinese Medicine
Introduction: The compatibility of Traditional Chinese Medicine (TCM) holds the potential for reducing toxicity and enhancing efficacy, serving as a crucial guide for the clinical application of TCM.
Qiwu Jiang, Suhan Yang, Shan He, Fei Li
doaj   +1 more source

Sports and Chinese herbal medicine

Pharmacological Research - Modern Chinese Medicine, 2023
Background: Chinese herbs have been used in sports and exercises as potent remedies for the treatment of sports injuries and recovery from sports fatigue. Herbs such as Astragalus, Radix Codonopsis, Shiitake and Rhodiola are favoured for their ability to
ZeHua Yu, WenBin Wang, Kun Yang, JinFei Gou, Yi Jiang, ZhangBiao Yu   +5 more
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Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

When the East Meets the West: the Future of Traditional Chinese Medicine in the 21st Century

康复学报, 2016
Traditional Chinese medicine (TCM) has a history of thousands of years, is a very valuable treasure left by our ancestors, and there are many things which are worth our in-depth mining. But in the past hundreds of years, with the Western medicine came to
Jin QIU
doaj  

SChLAP1 contributes to non-small cell lung cancer cell progression and immune evasion through regulating the AUF1/PD-L1 axis

Autoimmunity, 2021
SChLAP1 is recently reported as a key oncogenic long non-coding RNA in human cancer. However, whether SChLAP1 functions in non-small cell lung cancer (NSCLC) and its specific potential regulatory mechanism remain unexplored.
Zhonghai Du, Shuxian Niu, Juan Wang, Jun Wu, Sheng Li, Xiuxiu Yi   +5 more
doaj   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Clinical Practice Guidelines of Chinese Medicine Rehabilitation for Ischemic Stroke （Cerebral Infarction）Working Group of Clinical Practice Guidelines of Chinese Medicine Rehabilitation for Ischemic Stroke (Cerebral Infarction)

康复学报, 2021
Ischemic stroke (cerebral infarction) is a common clinical disease of ischemic necrosis or softening of localized brain tissue, which belongs to "stroke disease" in traditional Chinese medicine (TCM).
Working Group of Clinical Practice Guidelines of Chinese Medicine Rehabilitation for Ischemic Stroke (Cerebral Infarction)
doaj  

TCM-Grid: Weaving a Medical Grid for Traditional Chinese Medicine [PDF]

, 2003
We present a TCM-Grid for Traditional Chinese Medicine (TCM). The purpose of the TCM-Grid is to aid the development of distributed systems that help health professionals, researchers, enterprizes and personal users to retrieve, integrate and share TCM information and knowledge from geographically decentralized TCM database resources and knowledge base ...
Huajun Chen, Zhaohui Wu 0001, Chang Huang, Jiefeng Xu   +3 more
openaire   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source