Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Chromatographic Method for Monitoring of Pesticide Residues and Risk Assessment for Herbal Decoctions Used in Traditional Korean Medicine Clinics. [PDF]
Molecules, 2023 Kang SM +6 more
europepmc +1 more source
Advanced Science, EarlyView.This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
Utilization of Traditional Korean Medicine Services by the Older Population: A Cross-Sectional Study. [PDF]
Healthcare (Basel), 2022 Sung AD +8 more
europepmc +1 more source
Division of Household Labor and Marital Satisfaction in China, Japan, and Korea [PDF]
In this study, we compare the association of marital satisfaction with the division of labor between husband and wife in Asia, based on Chinese, Japanese, and Korean General Social Surveys in 2006 (N = 2,346, 997, and 990, respectively).
Kobayashi, Miki +2 more
core
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Effect of Traditional Korean Medicine Oncotherapy on the Survival, Quality of Life, and Telomere Length: A Prospective Cohort Study. [PDF]
Integr Cancer Ther, 2023 Ha SJ +5 more
europepmc +1 more source
Unpaired Learning‐Enabled Nanotube Identification from AFM Images
Advanced Science, EarlyView.Identifying nanotubes on rough substrates is notoriously challenging for conventional image analysis. This work presents an unpaired deep learning approach that automatically extracts nanotube networks from atomic force microscopy images, even on complex polymeric surfaces used in roll‐to‐roll printing.
Soyoung Na +10 more
wiley +1 more source
Socio-economic and Demographic factors affecting the likelihood of being an overweight Korean woman [PDF]
Using data from urban Korean women survey the study examines factors associated with the BMI >= 25, indicating overweight or obesity. Logit equation results identify low income, low education, household location and preference for convenience, sweet ...
Florkowski, Wojciech J. +2 more
core +1 more source
Biodegradable Adhesive Systems for Bio‐Integrated Applications
Advanced Science, EarlyView.Biodegradable adhesives provide temporary yet reliable adhesion while degrading into safe, non‐toxic by‐products under physiological or environmental conditions. This review summarizes recent developments in physical and chemical adhesion mechanisms—including hydrogen bonding, catechol chemistry, amine‐carboxyl coupling, and emerging diazirine and urea
Won Bae Han +6 more
wiley +1 more source