Results 41 to 50 of about 2,601,429 (305)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Rethinking Nigeria’s Development Using African Traditional Communication Media for National Orientation [PDF]

open access: yes, 2018
This paper examines the problem of poor orientation of most Nigerian citizens, especially the rural dwellers, occasioned by the dearth and failure of modern media in rural Nigeria; a phenomenon that has led to a major setback in participatory governance ...
Iyorza, Stanislaus
core  

Combining Search, Social Media, and Traditional Data Sources to Improve Influenza Surveillance

open access: yes, 2015
We present a machine learning-based methodology capable of providing real-time ("nowcast") and forecast estimates of influenza activity in the US by leveraging data from multiple data sources including: Google searches, Twitter microblogs, nearly real ...
André T Nguyen   +5 more
core   +2 more sources

Tac-tiles: multimodal pie charts for visually impaired users [PDF]

open access: yes, 2006
Tac-tiles is an accessible interface that allows visually impaired users to browse graphical information using tactile and audio feedback. The system uses a graphics tablet which is augmented with a tangible overlay tile to guide user exploration ...
Brewster, S.A., Wall, S.A.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Information sources in Kosovo – traditional media vs. new media [PDF]

open access: yes, 2014
The information in the digital era has become diverse and redundant. The individual in society gets hundreds and thousands of messages in different ways and channels of communication, but at the end of the day, they remember the most important ones.
Rexhepi, Zija
core  

Non-traditional Calculations of Elementary Mathematical Operations: Part 1. Multiplication and Division [PDF]

open access: yes, 2018
Different computational systems are a set of functional units and processors that can work together and exchange data with each other if required. In most cases, data transmission is organized in such a way that enables for the possibility of connecting ...
Filippenko, I. (Igor)
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

CULTURAL TRANSLATION OF TRADITIONAL FOOD FROM WEST-JAVA: A MEDIA TO PROMOTE THE TRADITIONAL CUISINE TO THE WORLD [PDF]

open access: yes, 2017
Indonesia is the largest archipelagic country in the world with a total of 17,054 islands. Each island has different customs, values and habits. As one of the elements of culture,Indonesian culinary is also a pride cultural element.
Amalia, Rosaria Mita
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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